Comprehensive FISH probe design tool applied to imaging human immunoglobulin class switch recombination.
We present a web engine boosted fluorescence in-situ hybridization (webFISH) algorithm using a genome-wide sequence similarity search to design target-specific single-copy and repetitive DNA FISH probes. The webFISH algorithm featuring a user-friendly interface (http://www.webfish2.org/) maximizes t...
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| Main Authors: | Jakub Nedbal, Philip S Hobson, David J Fear, Rainer Heintzmann, Hannah J Gould |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0051675&type=printable |
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