RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMA
The intraoperative radiation therapy (IORT) in combined therapy of soft tissue sarcoma in a single dose 10–20 Gy is the method, which can optimize the role of radiation therapy in treatment of this nosology. This method allows exact localization of the irradiation zone in the frames of «tumor bed»,...
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| Format: | Article |
| Language: | Russian |
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Pavlov First Saint Petersburg State Medical University
2018-01-01
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| Series: | Вестник хирургии имени И.И. Грекова |
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| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/771 |
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| author | P. A. Ott A. V. Privalov A. V. Vazhenin N. A. Chekha E. G. Zabolotskaya A. V. Komissarov |
| author_facet | P. A. Ott A. V. Privalov A. V. Vazhenin N. A. Chekha E. G. Zabolotskaya A. V. Komissarov |
| author_sort | P. A. Ott |
| collection | DOAJ |
| description | The intraoperative radiation therapy (IORT) in combined therapy of soft tissue sarcoma in a single dose 10–20 Gy is the method, which can optimize the role of radiation therapy in treatment of this nosology. This method allows exact localization of the irradiation zone in the frames of «tumor bed», thereby minimizing the damage of normal tissues and critical organs. The aim of the study was the influence of IORT on the rate and structure of postoperative complications and long-term results of treatment in the group under study (n=49) in comparison with the group of combined treatment without IORT (n=57) and the group of surgical treatment. No statistically reliable difference in the rate of postoperative complications in groups (p=0.57) was obtained and there was no influence on the structure of postoperative complications. At the same time the statistically reliable increase of general survival rates (p=0.025) and the survival without relapse in the main group (p |
| format | Article |
| id | doaj-art-82c19a35d8144e288ded755bd0c4aa86 |
| institution | Kabale University |
| issn | 0042-4625 |
| language | Russian |
| publishDate | 2018-01-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj-art-82c19a35d8144e288ded755bd0c4aa862025-08-20T04:00:34ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252018-01-01172109910110.24884/0042-4625-2013-172-1-099-101770RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMAP. A. Ott0A. V. Privalov1A. V. Vazhenin2N. A. Chekha3E. G. Zabolotskaya4A. V. Komissarov5The state budget institution of public health «Regional oncologic dispensary № 2»The Chelyabinsk district clinical oncologic dispensaryThe Chelyabinsk district clinical oncologic dispensaryThe state budget institution of public health «Regional oncologic dispensary № 2»The state budget institution of public health «Regional oncologic dispensary № 2»The state budget institution of public health «Regional oncologic dispensary № 2»The intraoperative radiation therapy (IORT) in combined therapy of soft tissue sarcoma in a single dose 10–20 Gy is the method, which can optimize the role of radiation therapy in treatment of this nosology. This method allows exact localization of the irradiation zone in the frames of «tumor bed», thereby minimizing the damage of normal tissues and critical organs. The aim of the study was the influence of IORT on the rate and structure of postoperative complications and long-term results of treatment in the group under study (n=49) in comparison with the group of combined treatment without IORT (n=57) and the group of surgical treatment. No statistically reliable difference in the rate of postoperative complications in groups (p=0.57) was obtained and there was no influence on the structure of postoperative complications. At the same time the statistically reliable increase of general survival rates (p=0.025) and the survival without relapse in the main group (phttps://www.vestnik-grekova.ru/jour/article/view/771саркомы мягких тканейинтраоперационная лучевая терапиякомбинированное лечениеsoft tissue sarcomaintraoperative radiation therapycombined treatment |
| spellingShingle | P. A. Ott A. V. Privalov A. V. Vazhenin N. A. Chekha E. G. Zabolotskaya A. V. Komissarov RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMA Вестник хирургии имени И.И. Грекова саркомы мягких тканей интраоперационная лучевая терапия комбинированное лечение soft tissue sarcoma intraoperative radiation therapy combined treatment |
| title | RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMA |
| title_full | RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMA |
| title_fullStr | RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMA |
| title_full_unstemmed | RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMA |
| title_short | RESULTS OF COMBINED TREATMENT WITH INTRAOPERATIVE RADIAL THERAPY OF SOFT TISSUE SARCOMA |
| title_sort | results of combined treatment with intraoperative radial therapy of soft tissue sarcoma |
| topic | саркомы мягких тканей интраоперационная лучевая терапия комбинированное лечение soft tissue sarcoma intraoperative radiation therapy combined treatment |
| url | https://www.vestnik-grekova.ru/jour/article/view/771 |
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