Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysis

Groundwater contamination is a significant global challenge, particularly in arid and semi-arid regions where groundwater is a primary source for drinking and irrigation. This contamination is closely associated with human health risks, potentially leading to severe diseases and long-term health con...

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Main Authors: Musaab A.A. Mohammed, Norbert P. Szabó, Elamin D. Suliman, Magboul M.S. Siddig, Mohammed N.M. Hassan, Péter Szűcs
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Environmental Challenges
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667010025000952
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author Musaab A.A. Mohammed
Norbert P. Szabó
Elamin D. Suliman
Magboul M.S. Siddig
Mohammed N.M. Hassan
Péter Szűcs
author_facet Musaab A.A. Mohammed
Norbert P. Szabó
Elamin D. Suliman
Magboul M.S. Siddig
Mohammed N.M. Hassan
Péter Szűcs
author_sort Musaab A.A. Mohammed
collection DOAJ
description Groundwater contamination is a significant global challenge, particularly in arid and semi-arid regions where groundwater is a primary source for drinking and irrigation. This contamination is closely associated with human health risks, potentially leading to severe diseases and long-term health consequences. In this study, the groundwater quality of the Nubian Aquifer System (NAS) in the Shendi area, Sudan, is assessed to evaluate health risks linked to nitrogen compounds (NO₂, NO₃, NH₃) and fluoride (F). The analysis integrates self-organizing maps (SOM), principal component analysis (PCA), and Monte Carlo-based health risk simulations. SOM analysis revealed distinct clustering patterns in groundwater samples, identifying three major hydrochemical trends. PCA indicated that elevated NO₃ concentrations were localized, primarily associated with agricultural runoff, while NO₂ and NH₃ reflected pollution from both agriculture and wastewater. High fluoride concentrations were linked to geogenic sources, particularly water-rock interactions with fluorine-bearing minerals. The Monte Carlo simulation assessed probabilistic health risks, revealing higher mean hazard quotients (HQs) and hazard index (HI) values for children compared to adults. Children’s mean HI of 1.06 significantly exceeds the safe threshold, indicating potential non-carcinogenic health hazards. Sobol sensitivity analysis identified the most influential parameters in shaping health risks, including average exposure time, body weight, and exposure duration, with strong parameter interactions amplifying these effects. Among contaminants, NO₃ and F contributed the most to cumulative HI values. These findings underscore the urgent need for targeted interventions, such as advanced water treatment, stricter pollution controls, and public health awareness programs to mitigate groundwater contamination and protect vulnerable populations.
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spelling doaj-art-82becf1a956c4745ac2f38bf8ad2cd702025-08-20T03:53:12ZengElsevierEnvironmental Challenges2667-01002025-09-012010117610.1016/j.envc.2025.101176Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysisMusaab A.A. Mohammed0Norbert P. Szabó1Elamin D. Suliman2Magboul M.S. Siddig3Mohammed N.M. Hassan4Péter Szűcs5Faculty of Earth and Environmental Sciences and Engineering, University of Miskolc, 3515 Miskolc, Egyetemváros, Hungary; College of Petroleum Geology and Minerals, University of Bahri, Khartoum, Sudan; Corresponding author.Faculty of Earth and Environmental Sciences and Engineering, University of Miskolc, 3515 Miskolc, Egyetemváros, HungaryFaculty of Minerals and Earth Sciences, Nile Valley University, Nile River State, SudanDepartment of Soil and Environment Sciences, Faculty of Agriculture, University of Khartoum, Khartoum, Sudan; Department of Physical Geography, University of Göttingen, 37077, Göttingen, GermanyFaculty of Petroleum and Minerals, Al-Neelain University, Khartoum, SudanFaculty of Earth and Environmental Sciences and Engineering, University of Miskolc, 3515 Miskolc, Egyetemváros, HungaryGroundwater contamination is a significant global challenge, particularly in arid and semi-arid regions where groundwater is a primary source for drinking and irrigation. This contamination is closely associated with human health risks, potentially leading to severe diseases and long-term health consequences. In this study, the groundwater quality of the Nubian Aquifer System (NAS) in the Shendi area, Sudan, is assessed to evaluate health risks linked to nitrogen compounds (NO₂, NO₃, NH₃) and fluoride (F). The analysis integrates self-organizing maps (SOM), principal component analysis (PCA), and Monte Carlo-based health risk simulations. SOM analysis revealed distinct clustering patterns in groundwater samples, identifying three major hydrochemical trends. PCA indicated that elevated NO₃ concentrations were localized, primarily associated with agricultural runoff, while NO₂ and NH₃ reflected pollution from both agriculture and wastewater. High fluoride concentrations were linked to geogenic sources, particularly water-rock interactions with fluorine-bearing minerals. The Monte Carlo simulation assessed probabilistic health risks, revealing higher mean hazard quotients (HQs) and hazard index (HI) values for children compared to adults. Children’s mean HI of 1.06 significantly exceeds the safe threshold, indicating potential non-carcinogenic health hazards. Sobol sensitivity analysis identified the most influential parameters in shaping health risks, including average exposure time, body weight, and exposure duration, with strong parameter interactions amplifying these effects. Among contaminants, NO₃ and F contributed the most to cumulative HI values. These findings underscore the urgent need for targeted interventions, such as advanced water treatment, stricter pollution controls, and public health awareness programs to mitigate groundwater contamination and protect vulnerable populations.http://www.sciencedirect.com/science/article/pii/S2667010025000952Human healthSelf-organizing mapPrincipal componentsMonte CarloSobol analysisGroundwater quality
spellingShingle Musaab A.A. Mohammed
Norbert P. Szabó
Elamin D. Suliman
Magboul M.S. Siddig
Mohammed N.M. Hassan
Péter Szűcs
Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysis
Environmental Challenges
Human health
Self-organizing map
Principal components
Monte Carlo
Sobol analysis
Groundwater quality
title Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysis
title_full Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysis
title_fullStr Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysis
title_full_unstemmed Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysis
title_short Integrated assessment of human health risks from groundwater pollutants in Nubian Aquifer, Sudan: Combining source apportionment and probabilistic analysis
title_sort integrated assessment of human health risks from groundwater pollutants in nubian aquifer sudan combining source apportionment and probabilistic analysis
topic Human health
Self-organizing map
Principal components
Monte Carlo
Sobol analysis
Groundwater quality
url http://www.sciencedirect.com/science/article/pii/S2667010025000952
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