Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment
<b>Introduction</b>: This study aims to investigate the relationship between olfactory identification (OI) and cognitive impairment by examining OI abilities across various stages of cognitive deterioration. <b>Methods</b>: A total of 264 participants were divided into three...
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MDPI AG
2024-11-01
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| Series: | European Journal of Investigation in Health, Psychology and Education |
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| Online Access: | https://www.mdpi.com/2254-9625/14/12/196 |
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| author | Jaime Bouhaben Alice Helena Delgado-Lima María Luisa Delgado-Losada |
| author_facet | Jaime Bouhaben Alice Helena Delgado-Lima María Luisa Delgado-Losada |
| author_sort | Jaime Bouhaben |
| collection | DOAJ |
| description | <b>Introduction</b>: This study aims to investigate the relationship between olfactory identification (OI) and cognitive impairment by examining OI abilities across various stages of cognitive deterioration. <b>Methods</b>: A total of 264 participants were divided into three groups based on cognitive status: cognitively healthy, subjective cognitive, and mild cognitive impairment. All participants were assessed using the Sniffin’ Sticks Olfactory Identification test and a comprehensive neuropsychological test battery. <b>Results</b>: Our results highlight the main effects of age and cognitive status on OI scores. Regarding cognitive abilities, OI is associated with measures of short-term memory, long-term, working memory, and selective attention. Finally, logistic regression models showed that OI is a significant predictor for discriminating SCD from CH, MCI from CH, and MCI from SCD. <b>Discussion</b>: These findings suggest the addition of olfactory identification measures in neuropsychological assessments could improve the early detection of individuals at risk for cognitive impairment. |
| format | Article |
| id | doaj-art-82be5c76ab0d4c09952a685e9bb6cb33 |
| institution | DOAJ |
| issn | 2174-8144 2254-9625 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | European Journal of Investigation in Health, Psychology and Education |
| spelling | doaj-art-82be5c76ab0d4c09952a685e9bb6cb332025-08-20T02:56:06ZengMDPI AGEuropean Journal of Investigation in Health, Psychology and Education2174-81442254-96252024-11-0114122978300010.3390/ejihpe14120196Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive ImpairmentJaime Bouhaben0Alice Helena Delgado-Lima1María Luisa Delgado-Losada2Experimental Psychology, Cognitive Processes and Speech Therapy Department, Faculty of Psychology, Complutense University of Madrid, 28223 Pozuelo de Alarcón, SpainExperimental Psychology, Cognitive Processes and Speech Therapy Department, Faculty of Psychology, Complutense University of Madrid, 28223 Pozuelo de Alarcón, SpainExperimental Psychology, Cognitive Processes and Speech Therapy Department, Faculty of Psychology, Complutense University of Madrid, 28223 Pozuelo de Alarcón, Spain<b>Introduction</b>: This study aims to investigate the relationship between olfactory identification (OI) and cognitive impairment by examining OI abilities across various stages of cognitive deterioration. <b>Methods</b>: A total of 264 participants were divided into three groups based on cognitive status: cognitively healthy, subjective cognitive, and mild cognitive impairment. All participants were assessed using the Sniffin’ Sticks Olfactory Identification test and a comprehensive neuropsychological test battery. <b>Results</b>: Our results highlight the main effects of age and cognitive status on OI scores. Regarding cognitive abilities, OI is associated with measures of short-term memory, long-term, working memory, and selective attention. Finally, logistic regression models showed that OI is a significant predictor for discriminating SCD from CH, MCI from CH, and MCI from SCD. <b>Discussion</b>: These findings suggest the addition of olfactory identification measures in neuropsychological assessments could improve the early detection of individuals at risk for cognitive impairment.https://www.mdpi.com/2254-9625/14/12/196olfactionneuroplasticityagingsubjective cognitive declinecognitive impairmentmild cognitive impairment |
| spellingShingle | Jaime Bouhaben Alice Helena Delgado-Lima María Luisa Delgado-Losada Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment European Journal of Investigation in Health, Psychology and Education olfaction neuroplasticity aging subjective cognitive decline cognitive impairment mild cognitive impairment |
| title | Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment |
| title_full | Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment |
| title_fullStr | Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment |
| title_full_unstemmed | Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment |
| title_short | Olfactory Identification as a Biomarker for Cognitive Impairment: Insights from Healthy Aging, Subjective Cognitive Decline, and Mild Cognitive Impairment |
| title_sort | olfactory identification as a biomarker for cognitive impairment insights from healthy aging subjective cognitive decline and mild cognitive impairment |
| topic | olfaction neuroplasticity aging subjective cognitive decline cognitive impairment mild cognitive impairment |
| url | https://www.mdpi.com/2254-9625/14/12/196 |
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