Optogenetic storage and release of protein and mRNA in live cells and animals

Optogenetic storage and release of protein and mRNA in live cells and animals

Abstract Cells compartmentalize biomolecules in membraneless structures called biomolecular condensates. While their roles in regulating cellular processes are increasingly understood, tools for their synthetic manipulation remain limited. Here, we introduce RELISR (Reversible Light-Induced Store an...

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Bibliographic Details
Main Authors: Chaeyeon Lee, Jeonghye Yu, Jongpil Shin, Jihwan Yu, Yungyeong Heo, Moosung Lee, Daseuli Yu, YongKeun Park, Won Do Heo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61322-y
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