P25 | RESPONSE TO HEDGEHOG AND PI3K/AKT/MTOR PATHWAY INHIBITORS IN PREB-ALL: ANALYSIS OF THE INTRACELLULAR DISTRIBUTION OF PATHWAY ENZYMES AND OF THE AUTOPHAGY PROCESS

PreB-Acute Lymphoblastic Leukemia (ALL) is characterized by the uncontrolled proliferation of lymphoid precursors and the dysregulation of key intracellular signaling pathways. Among these, the PI3K/AKT/mTOR and Hedgehog (Hh) pathways play critical roles in promoting leukemic cell growth, survival,...

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Format: Article
Language:English
Published: PAGEPress Publications 2025-08-01
Series:European Journal of Histochemistry
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Online Access:https://www.ejh.it/ejh/article/view/4345
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