Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case Report
Background. Congenital syphilis is an intrauterine infection characterized by multiple organ damage with severe consequences leading to disability. Transmission of infection from mother to fetus can occur in utero through the placenta or during childbirth through direct contact with the infected bir...
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Union of pediatricians of Russia
2025-07-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/2644 |
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| author | Nailya R. Pimenova Elena I. Kashirskaya Oksana V. Lebedeva Dmitriy A. Molev O. A. Tyurina Anastasiya V. Alekseeva Daria E. Ushenina |
| author_facet | Nailya R. Pimenova Elena I. Kashirskaya Oksana V. Lebedeva Dmitriy A. Molev O. A. Tyurina Anastasiya V. Alekseeva Daria E. Ushenina |
| author_sort | Nailya R. Pimenova |
| collection | DOAJ |
| description | Background. Congenital syphilis is an intrauterine infection characterized by multiple organ damage with severe consequences leading to disability. Transmission of infection from mother to fetus can occur in utero through the placenta or during childbirth through direct contact with the infected birth canal of the mother. Early congenital syphilis in children under 2 years of age can occur in a latent form without clinical signs with positive serological reactions and in a manifest form with variable clinical symptoms. For the prevention of congenital syphilis, it is extremely important to screen pregnant women for the presence of the causative agent of the disease, as well as timely and full-fledged treatment of expectant mothers in case of positive results, which in most cases avoids infection of the fetus.Case Report. In the presented case report, a premature baby was born to a woman with untreated syphilis, confirmed serologically by a blood test at late pregnancy. From birth, the child showed signs of intrauterine infection with predominant liver damage. Pneumonia was diagnosed on the 7th day of life. X-ray examination of the tubular bones revealed signs of osteochondritis. Serological diagnostics revealed positive test results for syphilis and mycoplasmosis. The child received complex therapy (etiotropic, pathogenetic, symptomatic), against which positive dynamics was noted.Conclusion. In the described case report, infection of the fetus with Treponema pallidum and the manifestation of early congenital syphilis in the neonatal period in an active clinical form is probably due to the lack of preventive treatment of the mother during pregnancy. The presented data confirm the importance of the prevention of congenital syphilis, which should consist in the timely detection and treatment of the disease in expectant mothers. |
| format | Article |
| id | doaj-art-82a712b2454e431faacf8c33440623ce |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2025-07-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-82a712b2454e431faacf8c33440623ce2025-08-20T03:40:11ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892025-07-0122330130710.15690/pf.v22i3.29142195Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case ReportNailya R. Pimenova0Elena I. Kashirskaya1Oksana V. Lebedeva2Dmitriy A. Molev3O. A. Tyurina4Anastasiya V. Alekseeva5Daria E. Ushenina6Astrakhan State Medical UniversityAstrakhan State Medical UniversityAstrakhan State Medical UniversityN.N. Silishcheva Regional Children’s Clinical HospitalN.N. Silishcheva Regional Children’s Clinical HospitalAstrakhan State Medical UniversityAstrakhan State Medical UniversityBackground. Congenital syphilis is an intrauterine infection characterized by multiple organ damage with severe consequences leading to disability. Transmission of infection from mother to fetus can occur in utero through the placenta or during childbirth through direct contact with the infected birth canal of the mother. Early congenital syphilis in children under 2 years of age can occur in a latent form without clinical signs with positive serological reactions and in a manifest form with variable clinical symptoms. For the prevention of congenital syphilis, it is extremely important to screen pregnant women for the presence of the causative agent of the disease, as well as timely and full-fledged treatment of expectant mothers in case of positive results, which in most cases avoids infection of the fetus.Case Report. In the presented case report, a premature baby was born to a woman with untreated syphilis, confirmed serologically by a blood test at late pregnancy. From birth, the child showed signs of intrauterine infection with predominant liver damage. Pneumonia was diagnosed on the 7th day of life. X-ray examination of the tubular bones revealed signs of osteochondritis. Serological diagnostics revealed positive test results for syphilis and mycoplasmosis. The child received complex therapy (etiotropic, pathogenetic, symptomatic), against which positive dynamics was noted.Conclusion. In the described case report, infection of the fetus with Treponema pallidum and the manifestation of early congenital syphilis in the neonatal period in an active clinical form is probably due to the lack of preventive treatment of the mother during pregnancy. The presented data confirm the importance of the prevention of congenital syphilis, which should consist in the timely detection and treatment of the disease in expectant mothers.https://www.pedpharma.ru/jour/article/view/2644early congenital syphilisnewbornmycoplasma infectioncase report |
| spellingShingle | Nailya R. Pimenova Elena I. Kashirskaya Oksana V. Lebedeva Dmitriy A. Molev O. A. Tyurina Anastasiya V. Alekseeva Daria E. Ushenina Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case Report Педиатрическая фармакология early congenital syphilis newborn mycoplasma infection case report |
| title | Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case Report |
| title_full | Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case Report |
| title_fullStr | Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case Report |
| title_full_unstemmed | Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case Report |
| title_short | Manifest Form of Congenital Syphilis in Combination with Mycoplasma Infection in a Newborn Child: Case Report |
| title_sort | manifest form of congenital syphilis in combination with mycoplasma infection in a newborn child case report |
| topic | early congenital syphilis newborn mycoplasma infection case report |
| url | https://www.pedpharma.ru/jour/article/view/2644 |
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