Clinical validation of AI assisted animal ultrasound models for diagnosis of early liver trauma

Abstract The study aimed to develop an AI-assisted ultrasound model for early liver trauma identification, using data from Bama miniature pigs and patients in Beijing, China. A deep learning model was created and fine-tuned with animal and clinical data, achieving high accuracy metrics. In internal...

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Bibliographic Details
Main Authors: Qing Song, Xuelei He, Yanjie Wang, Hanjing Gao, Li Tan, Jun Ma, Linli Kang, Peng Han, Yukun Luo, Kun Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-91900-5
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Summary:Abstract The study aimed to develop an AI-assisted ultrasound model for early liver trauma identification, using data from Bama miniature pigs and patients in Beijing, China. A deep learning model was created and fine-tuned with animal and clinical data, achieving high accuracy metrics. In internal tests, the model outperformed both Junior and Senior sonographers. External tests showed the model’s effectiveness, with a Dice Similarity Coefficient of 0.74, True Positive Rate of 0.80, Positive Predictive Value of 0.74, and 95% Hausdorff distance of 14.84. The model’s performance was comparable to Junior sonographers and slightly lower than Senior sonographers. This AI model shows promise for liver injury detection, offering a valuable tool with diagnostic capabilities similar to those of less experienced human operators.
ISSN:2045-2322