The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement
The aim of this work is in the formulation of a dietary supplement, combining spirulina and date stone benefits. For this, a study was done on these two ingredients by determining their approximate composition and antioxidant potential. Following this, we used a statistical method to determine the a...
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| Format: | Article |
| Language: | English |
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Académie des sciences
2023-03-01
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| Series: | Comptes Rendus. Chimie |
| Subjects: | |
| Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.222/ |
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| author | Jabri Karoui, Iness Hammami, Majdi Abderrabba, Manef |
| author_facet | Jabri Karoui, Iness Hammami, Majdi Abderrabba, Manef |
| author_sort | Jabri Karoui, Iness |
| collection | DOAJ |
| description | The aim of this work is in the formulation of a dietary supplement, combining spirulina and date stone benefits. For this, a study was done on these two ingredients by determining their approximate composition and antioxidant potential. Following this, we used a statistical method to determine the appropriate proportions of ingredients to obtain a tablet with optimal physical properties. After setting these parameters, we analysed this tablet’s composition and effectiveness by evaluating its physicochemical properties, antioxidant potential, FTIR spectrum and studied the controlled release of phycocyanin. Our results revealed that the optimized formula showed high stability and richness in active compounds. |
| format | Article |
| id | doaj-art-8294609c2e194f0b9c3d49c93edde2bb |
| institution | Kabale University |
| issn | 1878-1543 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Académie des sciences |
| record_format | Article |
| series | Comptes Rendus. Chimie |
| spelling | doaj-art-8294609c2e194f0b9c3d49c93edde2bb2025-02-07T13:37:38ZengAcadémie des sciencesComptes Rendus. Chimie1878-15432023-03-0126S116918210.5802/crchim.22210.5802/crchim.222The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplementJabri Karoui, Iness0https://orcid.org/0000-0002-0597-9460Hammami, Majdi1https://orcid.org/0000-0002-4376-0638Abderrabba, Manef2https://orcid.org/0000-0002-1129-0539Laboratory of Materials Molecules and Applications, Preparatory Institute for Scientific and Technical Studies, Carthage University, B.P:51, La Marsa, 2075 Tunis, TunisiaLaboratory of Medicinal and Aromatic Plants Biotechnology Centre of Borj-Cedria BP 901, 2050, Hammam-Lif, TunisiaLaboratory of Materials Molecules and Applications, Preparatory Institute for Scientific and Technical Studies, Carthage University, B.P:51, La Marsa, 2075 Tunis, TunisiaThe aim of this work is in the formulation of a dietary supplement, combining spirulina and date stone benefits. For this, a study was done on these two ingredients by determining their approximate composition and antioxidant potential. Following this, we used a statistical method to determine the appropriate proportions of ingredients to obtain a tablet with optimal physical properties. After setting these parameters, we analysed this tablet’s composition and effectiveness by evaluating its physicochemical properties, antioxidant potential, FTIR spectrum and studied the controlled release of phycocyanin. Our results revealed that the optimized formula showed high stability and richness in active compounds.https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.222/Date stoneSpirulinaTabletsAntioxidant activityDietary supplementPhycocyanin |
| spellingShingle | Jabri Karoui, Iness Hammami, Majdi Abderrabba, Manef The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement Comptes Rendus. Chimie Date stone Spirulina Tablets Antioxidant activity Dietary supplement Phycocyanin |
| title | The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement |
| title_full | The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement |
| title_fullStr | The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement |
| title_full_unstemmed | The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement |
| title_short | The use of D-Optimal Mixture Design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement |
| title_sort | use of d optimal mixture design in the development of date stone and spirulina tablet formulation as a phycocyanin dietary supplement |
| topic | Date stone Spirulina Tablets Antioxidant activity Dietary supplement Phycocyanin |
| url | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.222/ |
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