Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial
Objective: To assess the effectiveness and safety of auricular acupressure in reducing the incidence of adverse reactions(ADRs) during the bowel preparation. Methods: This was a prospective, assessor-blinded, randomized controlled clinical trial implemented at Guangdong Provincial Hospital of Chines...
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Elsevier
2025-02-01
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025005675 |
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| author | Jiahui Zhang Chang Liu Guodong Ruan Haiyan Zhang Beiping Zhang Xuejun Hu Cailing Zhong |
| author_facet | Jiahui Zhang Chang Liu Guodong Ruan Haiyan Zhang Beiping Zhang Xuejun Hu Cailing Zhong |
| author_sort | Jiahui Zhang |
| collection | DOAJ |
| description | Objective: To assess the effectiveness and safety of auricular acupressure in reducing the incidence of adverse reactions(ADRs) during the bowel preparation. Methods: This was a prospective, assessor-blinded, randomized controlled clinical trial implemented at Guangdong Provincial Hospital of Chinese Medicine. Between October 2022 and February 2023, 190 hospitalized patients undergoing colonoscopy were randomly assigned to the intervention and control groups in a 1:1 ratio. The intervention group received auricular acupressure during bowel preparation, whereas the control group received no additional treatment. Analyses were conducted using the intention-to-treat method. Intervention effects were evaluated by comparing outcomes between the two groups. Results: The overall incidence of ADRs to bowel preparation in the intervention group (37/95 = 37.89 %) was lower than that in the control group (59/95 = 62.11 %, P < 0.05). Compared with control group, the incidence of nausea in the intervention group decreased by 15.79 %(95%CI 0.03–0.19, P = 0.018), whereas no significant difference was observed in the incidence of abdominal distension(P > 0.05). Regarding the comparison of the severity of the ADRs, the overall score of ADRs and the scores for nausea and abdominal distension in the intervention group were statistically lower than those in the control group (all P < 0.05). No auricular acupressure-related adverse effect was observed. Conclusions: Auricular acupressure can significantly decrease the incidence of ADRs to colonoscopic bowel preparation in patients and alleviate the severity of nausea and bloating symptoms, which is a safe, simple, and effective method. Trial registration: ChiCTR, no. ChiCTR2200061742; Registered July 2, 2022. URL: https://www.chictr.org.cn/showprojEN.html?proj=167796. |
| format | Article |
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| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
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| series | Heliyon |
| spelling | doaj-art-828e970469dc4fa186b17eb5003855dd2025-02-07T04:47:54ZengElsevierHeliyon2405-84402025-02-01113e42187Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trialJiahui Zhang0Chang Liu1Guodong Ruan2Haiyan Zhang3Beiping Zhang4Xuejun Hu5Cailing Zhong6Huangpu Hospital of Guangdong Second Traditional Chinese Medicine Hospital, Guangzhou, Guangdong, 510799, PR ChinaGuangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine), Guangzhou, Guangdong, 510120, PR ChinaGuangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine), Guangzhou, Guangdong, 510120, PR ChinaGuangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine), Guangzhou, Guangdong, 510120, PR ChinaGuangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine), Guangzhou, Guangdong, 510120, PR ChinaGuangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine), Guangzhou, Guangdong, 510120, PR China; Corresponding author. The Department of Gastroenterology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 111 Dade Road, Yuexiu District, Guangzhou, 510120, PR China.Guangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine), Guangzhou, Guangdong, 510120, PR China; Corresponding author. The Department of Gastroenterology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 111 Dade Road, Yuexiu District, Guangzhou, 510120, PR China.Objective: To assess the effectiveness and safety of auricular acupressure in reducing the incidence of adverse reactions(ADRs) during the bowel preparation. Methods: This was a prospective, assessor-blinded, randomized controlled clinical trial implemented at Guangdong Provincial Hospital of Chinese Medicine. Between October 2022 and February 2023, 190 hospitalized patients undergoing colonoscopy were randomly assigned to the intervention and control groups in a 1:1 ratio. The intervention group received auricular acupressure during bowel preparation, whereas the control group received no additional treatment. Analyses were conducted using the intention-to-treat method. Intervention effects were evaluated by comparing outcomes between the two groups. Results: The overall incidence of ADRs to bowel preparation in the intervention group (37/95 = 37.89 %) was lower than that in the control group (59/95 = 62.11 %, P < 0.05). Compared with control group, the incidence of nausea in the intervention group decreased by 15.79 %(95%CI 0.03–0.19, P = 0.018), whereas no significant difference was observed in the incidence of abdominal distension(P > 0.05). Regarding the comparison of the severity of the ADRs, the overall score of ADRs and the scores for nausea and abdominal distension in the intervention group were statistically lower than those in the control group (all P < 0.05). No auricular acupressure-related adverse effect was observed. Conclusions: Auricular acupressure can significantly decrease the incidence of ADRs to colonoscopic bowel preparation in patients and alleviate the severity of nausea and bloating symptoms, which is a safe, simple, and effective method. Trial registration: ChiCTR, no. ChiCTR2200061742; Registered July 2, 2022. URL: https://www.chictr.org.cn/showprojEN.html?proj=167796.http://www.sciencedirect.com/science/article/pii/S2405844025005675Auricular acupressureBowel preparationAdverse reactionsVaccaria segetalisRandomized controlled trialTraditional Chinese medicine |
| spellingShingle | Jiahui Zhang Chang Liu Guodong Ruan Haiyan Zhang Beiping Zhang Xuejun Hu Cailing Zhong Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial Heliyon Auricular acupressure Bowel preparation Adverse reactions Vaccaria segetalis Randomized controlled trial Traditional Chinese medicine |
| title | Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial |
| title_full | Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial |
| title_fullStr | Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial |
| title_full_unstemmed | Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial |
| title_short | Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial |
| title_sort | auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients a randomized controlled trial |
| topic | Auricular acupressure Bowel preparation Adverse reactions Vaccaria segetalis Randomized controlled trial Traditional Chinese medicine |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025005675 |
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