Options of biological substances application in rectal fistulas treatment (Review of the literature)

Aim of review. To present literature data of the treatment of incomplete rectal fistulas with application of biological substances. Summary. Treatment of rectal fistulas remains burning issue in coloproctology due to unsatisfactory results of surgery resulting in high relapse rate, usually regardles...

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Main Authors: A. M. Kuzminov, S. A. Frolov, D. V. Vyshegorodtsev, V. Yu. Korolik, Sh. T. Minbayev, I. S. Bogormistrov, M. O. Chernozhukova
Format: Article
Language:Russian
Published: Gastro LLC 2016-08-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/62
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author A. M. Kuzminov
S. A. Frolov
D. V. Vyshegorodtsev
V. Yu. Korolik
Sh. T. Minbayev
I. S. Bogormistrov
M. O. Chernozhukova
author_facet A. M. Kuzminov
S. A. Frolov
D. V. Vyshegorodtsev
V. Yu. Korolik
Sh. T. Minbayev
I. S. Bogormistrov
M. O. Chernozhukova
author_sort A. M. Kuzminov
collection DOAJ
description Aim of review. To present literature data of the treatment of incomplete rectal fistulas with application of biological substances. Summary. Treatment of rectal fistulas remains burning issue in coloproctology due to unsatisfactory results of surgery resulting in high relapse rate, usually regardless of applied surgical method and high risk of severe complications as anal sphincter incompetence. This is why development of sparing methods of rectal fistula treatment that will allow to decrease intraoperative trauma of the anal sphincter at minimal risk of disease recurrence and, therefore, to prevent development of sphincter incompetence is important. Application of biological materials in rectal fistulas treatment result in reduction of the wound size, accelerates reparative processes and decreases degree of traumatization. Minimization of surgical impact on the anal sphincter allows repetitive application of biological materials up to the achievement of positive effect. Conclusion. Application of biological materials at sphincter-preserving technique provides decreased risk of development of postoperative anal sphincter incompetence.
format Article
id doaj-art-8284d02e3897404ab7d580115b1d6172
institution Kabale University
issn 1382-4376
2658-6673
language Russian
publishDate 2016-08-01
publisher Gastro LLC
record_format Article
series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-8284d02e3897404ab7d580115b1d61722025-02-10T16:14:34ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732016-08-01263818610.22416/1382-4376-2016-26-3-81-8662Options of biological substances application in rectal fistulas treatment (Review of the literature)A. M. Kuzminov0S. A. Frolov1D. V. Vyshegorodtsev2V. Yu. Korolik3Sh. T. Minbayev4I. S. Bogormistrov5M. O. Chernozhukova6Federal government-financed institution «Ryzhikh state scientific center of coloproctology»Federal government-financed institution «Ryzhikh state scientific center of coloproctology»Federal government-financed institution «Ryzhikh state scientific center of coloproctology»Federal government-financed institution «Ryzhikh state scientific center of coloproctology»Federal government-financed institution «Ryzhikh state scientific center of coloproctology»Federal government-financed institution «Ryzhikh state scientific center of coloproctology»Federal government-financed institution «Ryzhikh state scientific center of coloproctology»Aim of review. To present literature data of the treatment of incomplete rectal fistulas with application of biological substances. Summary. Treatment of rectal fistulas remains burning issue in coloproctology due to unsatisfactory results of surgery resulting in high relapse rate, usually regardless of applied surgical method and high risk of severe complications as anal sphincter incompetence. This is why development of sparing methods of rectal fistula treatment that will allow to decrease intraoperative trauma of the anal sphincter at minimal risk of disease recurrence and, therefore, to prevent development of sphincter incompetence is important. Application of biological materials in rectal fistulas treatment result in reduction of the wound size, accelerates reparative processes and decreases degree of traumatization. Minimization of surgical impact on the anal sphincter allows repetitive application of biological materials up to the achievement of positive effect. Conclusion. Application of biological materials at sphincter-preserving technique provides decreased risk of development of postoperative anal sphincter incompetence.https://www.gastro-j.ru/jour/article/view/62свищ прямой кишкифибриновый клейколлагеновые имплантыплазма, обогащенная тромбоцитарными факторами ростааутологические стволовые клетки
spellingShingle A. M. Kuzminov
S. A. Frolov
D. V. Vyshegorodtsev
V. Yu. Korolik
Sh. T. Minbayev
I. S. Bogormistrov
M. O. Chernozhukova
Options of biological substances application in rectal fistulas treatment (Review of the literature)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
свищ прямой кишки
фибриновый клей
коллагеновые импланты
плазма, обогащенная тромбоцитарными факторами роста
аутологические стволовые клетки
title Options of biological substances application in rectal fistulas treatment (Review of the literature)
title_full Options of biological substances application in rectal fistulas treatment (Review of the literature)
title_fullStr Options of biological substances application in rectal fistulas treatment (Review of the literature)
title_full_unstemmed Options of biological substances application in rectal fistulas treatment (Review of the literature)
title_short Options of biological substances application in rectal fistulas treatment (Review of the literature)
title_sort options of biological substances application in rectal fistulas treatment review of the literature
topic свищ прямой кишки
фибриновый клей
коллагеновые импланты
плазма, обогащенная тромбоцитарными факторами роста
аутологические стволовые клетки
url https://www.gastro-j.ru/jour/article/view/62
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AT safrolov optionsofbiologicalsubstancesapplicationinrectalfistulastreatmentreviewoftheliterature
AT dvvyshegorodtsev optionsofbiologicalsubstancesapplicationinrectalfistulastreatmentreviewoftheliterature
AT vyukorolik optionsofbiologicalsubstancesapplicationinrectalfistulastreatmentreviewoftheliterature
AT shtminbayev optionsofbiologicalsubstancesapplicationinrectalfistulastreatmentreviewoftheliterature
AT isbogormistrov optionsofbiologicalsubstancesapplicationinrectalfistulastreatmentreviewoftheliterature
AT mochernozhukova optionsofbiologicalsubstancesapplicationinrectalfistulastreatmentreviewoftheliterature