A phase 1 safety and feasibility trial of a ketogenic diet plus standard of care for patients with recently diagnosed glioblastoma

A phase 1 safety and feasibility trial of a ketogenic diet plus standard of care for patients with recently diagnosed glioblastoma

Abstract Despite great interest, there is limited clinical evidence to support the use of a ketogenic diet (KD) for cancer patients. We conducted a single-arm phase 1 trial of a KD among patients with recently diagnosed glioblastoma (GBM) receiving standard-of-care (SOC) treatment. Adults with GBM w...

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Bibliographic Details
Main Authors: L. J. Amaral, Gillian Gresham, Sungjin Kim, Mourad Tighiouart, Thomas A. Nelson, Amelia Welborn, Laura Lockshon, Brandon Noorvash, Jeremy D. Rudnick, Scott A. Irwin, Stephen J. Freedland, Jethro Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Glioblastoma
Ketogenic diets
Ketosis
Warburg effect
Cancer metabolism
Supportive care
Online Access:https://doi.org/10.1038/s41598-025-06675-6
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