SemFedXAI: A Semantic Framework for Explainable Federated Learning in Healthcare

Federated Learning (FL) is emerging as an encouraging paradigm for AI model training in healthcare that enables collaboration among institutions without revealing sensitive information. The lack of transparency in federated models makes their deployment in healthcare settings more difficult, as know...

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Main Authors: Alba Amato, Dario Branco
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Information
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Online Access:https://www.mdpi.com/2078-2489/16/6/435
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author Alba Amato
Dario Branco
author_facet Alba Amato
Dario Branco
author_sort Alba Amato
collection DOAJ
description Federated Learning (FL) is emerging as an encouraging paradigm for AI model training in healthcare that enables collaboration among institutions without revealing sensitive information. The lack of transparency in federated models makes their deployment in healthcare settings more difficult, as knowledge of the decision process is of primary importance. This paper introduces SemFedXAI, a new framework that combines Semantic Web technologies and federated learning to achieve better explainability of artificial intelligence models in healthcare. SemFedXAI extends traditional FL architectures with three key components: (1) Ontology-Enhanced Federated Learning that enriches models with domain knowledge, (2) a Semantic Aggregation Mechanism that uses semantic technologies to improve the consistency and interpretability of federated models, and (3) a Knowledge Graph-Based Explanation component that provides contextualized explanations of model decisions. We evaluated SemFedXAI within the context of e-health, reporting noteworthy advancements in explanation quality and predictive performance compared to conventional federated learning methods. The findings refer to the prospects of combining semantic technologies and federated learning as an avenue for building more explainable and resilient AI systems in healthcare.
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spelling doaj-art-82747246ae1e4eb0894dd6f2ac2df7632025-08-20T02:20:58ZengMDPI AGInformation2078-24892025-05-0116643510.3390/info16060435SemFedXAI: A Semantic Framework for Explainable Federated Learning in HealthcareAlba Amato0Dario Branco1Department of Political Science, University of Campania “L. Vanvitelli”, 81100 Caserta, ItalyDepartment of Engineering, University of Campania “L. Vanvitelli”, 81031 Aversa, ItalyFederated Learning (FL) is emerging as an encouraging paradigm for AI model training in healthcare that enables collaboration among institutions without revealing sensitive information. The lack of transparency in federated models makes their deployment in healthcare settings more difficult, as knowledge of the decision process is of primary importance. This paper introduces SemFedXAI, a new framework that combines Semantic Web technologies and federated learning to achieve better explainability of artificial intelligence models in healthcare. SemFedXAI extends traditional FL architectures with three key components: (1) Ontology-Enhanced Federated Learning that enriches models with domain knowledge, (2) a Semantic Aggregation Mechanism that uses semantic technologies to improve the consistency and interpretability of federated models, and (3) a Knowledge Graph-Based Explanation component that provides contextualized explanations of model decisions. We evaluated SemFedXAI within the context of e-health, reporting noteworthy advancements in explanation quality and predictive performance compared to conventional federated learning methods. The findings refer to the prospects of combining semantic technologies and federated learning as an avenue for building more explainable and resilient AI systems in healthcare.https://www.mdpi.com/2078-2489/16/6/435federated learningexplainable AIsemantic webknowledge managementhealthcareontologies
spellingShingle Alba Amato
Dario Branco
SemFedXAI: A Semantic Framework for Explainable Federated Learning in Healthcare
Information
federated learning
explainable AI
semantic web
knowledge management
healthcare
ontologies
title SemFedXAI: A Semantic Framework for Explainable Federated Learning in Healthcare
title_full SemFedXAI: A Semantic Framework for Explainable Federated Learning in Healthcare
title_fullStr SemFedXAI: A Semantic Framework for Explainable Federated Learning in Healthcare
title_full_unstemmed SemFedXAI: A Semantic Framework for Explainable Federated Learning in Healthcare
title_short SemFedXAI: A Semantic Framework for Explainable Federated Learning in Healthcare
title_sort semfedxai a semantic framework for explainable federated learning in healthcare
topic federated learning
explainable AI
semantic web
knowledge management
healthcare
ontologies
url https://www.mdpi.com/2078-2489/16/6/435
work_keys_str_mv AT albaamato semfedxaiasemanticframeworkforexplainablefederatedlearninginhealthcare
AT dariobranco semfedxaiasemanticframeworkforexplainablefederatedlearninginhealthcare