Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA
Abstract Background The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA. Methods A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug...
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SAGE Publishing
2020-12-01
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| Series: | Journal of Otolaryngology - Head and Neck Surgery |
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| Online Access: | https://doi.org/10.1186/s40463-020-00478-7 |
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| author | Ming-Chin Lan Stanley Yung-Chuan Liu Ming-Ying Lan Yun-Chen Huang Tung-Tsun Huang Yen-Bin Hsu |
| author_facet | Ming-Chin Lan Stanley Yung-Chuan Liu Ming-Ying Lan Yun-Chen Huang Tung-Tsun Huang Yen-Bin Hsu |
| author_sort | Ming-Chin Lan |
| collection | DOAJ |
| description | Abstract Background The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA. Methods A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug-induced Sleep Endoscopy) was carried out at a tertiary academic medical center. The factors correlating with positional and non-positional OSA were analyzed, including clinical characteristics, polysomnography data, and DISE findings. Results Univariate analysis revealed that non-positional dependency was correlated with a higher BMI (p < 0.001), neck circumference (p < 0.001), modified Mallampati score (p = 0.003), AHI (p < 0.001), degree of velum concentric collapse (p = 0.004), degree of oropharyngeal lateral wall collapse (p < 0.001), and degree of tongue base anteroposterior collapse (p = 0.004). Multivariate analysis revealed that oropharyngeal lateral wall collapse (OR = 1.90, p = 0.027) was the only anatomical factor significantly predicted non-positional dependency in OSA patients. AHI (OR = 1.04, p < 0.001), although significant, made only a marginal contribution to the prediction of non-positional dependency. Conclusions Oropharyngeal lateral wall collapse was identified as the only anatomical predictor for non-positional dependency in OSA patients. Therefore, further treatment modalities should address the distinct anatomical trait between positional and non-positional OSA. Graphical abstract |
| format | Article |
| id | doaj-art-82741896f8e9488f8ac417a1b6b0b17b |
| institution | Kabale University |
| issn | 1916-0216 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Otolaryngology - Head and Neck Surgery |
| spelling | doaj-art-82741896f8e9488f8ac417a1b6b0b17b2025-02-03T10:53:56ZengSAGE PublishingJournal of Otolaryngology - Head and Neck Surgery1916-02162020-12-014911710.1186/s40463-020-00478-7Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSAMing-Chin Lan0Stanley Yung-Chuan Liu1Ming-Ying Lan2Yun-Chen Huang3Tung-Tsun Huang4Yen-Bin Hsu5Department of Otolaryngology-Head & Neck Surgery, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical FoundationDivision of Sleep Surgery, Department of Otolaryngology, Stanford University School of MedicineDepartment of Otolaryngology-Head & Neck Surgery, Taipei Veterans General HospitalDepartment of Otolaryngology-Head & Neck Surgery, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical FoundationDepartment of Otolaryngology-Head & Neck Surgery, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical FoundationDepartment of Otolaryngology-Head & Neck Surgery, Taipei Veterans General HospitalAbstract Background The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA. Methods A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug-induced Sleep Endoscopy) was carried out at a tertiary academic medical center. The factors correlating with positional and non-positional OSA were analyzed, including clinical characteristics, polysomnography data, and DISE findings. Results Univariate analysis revealed that non-positional dependency was correlated with a higher BMI (p < 0.001), neck circumference (p < 0.001), modified Mallampati score (p = 0.003), AHI (p < 0.001), degree of velum concentric collapse (p = 0.004), degree of oropharyngeal lateral wall collapse (p < 0.001), and degree of tongue base anteroposterior collapse (p = 0.004). Multivariate analysis revealed that oropharyngeal lateral wall collapse (OR = 1.90, p = 0.027) was the only anatomical factor significantly predicted non-positional dependency in OSA patients. AHI (OR = 1.04, p < 0.001), although significant, made only a marginal contribution to the prediction of non-positional dependency. Conclusions Oropharyngeal lateral wall collapse was identified as the only anatomical predictor for non-positional dependency in OSA patients. Therefore, further treatment modalities should address the distinct anatomical trait between positional and non-positional OSA. Graphical abstracthttps://doi.org/10.1186/s40463-020-00478-7Obstructive sleep apneaPositional OSANon-positional OSASleep positionPositional dependencyNon-positional dependency |
| spellingShingle | Ming-Chin Lan Stanley Yung-Chuan Liu Ming-Ying Lan Yun-Chen Huang Tung-Tsun Huang Yen-Bin Hsu Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA Journal of Otolaryngology - Head and Neck Surgery Obstructive sleep apnea Positional OSA Non-positional OSA Sleep position Positional dependency Non-positional dependency |
| title | Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA |
| title_full | Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA |
| title_fullStr | Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA |
| title_full_unstemmed | Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA |
| title_short | Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA |
| title_sort | role of drug induced sleep endoscopy in evaluation of positional vs non positional osa |
| topic | Obstructive sleep apnea Positional OSA Non-positional OSA Sleep position Positional dependency Non-positional dependency |
| url | https://doi.org/10.1186/s40463-020-00478-7 |
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