Distinctive autophagy/mitophagy biomarker profiles in frontotemporal lobar degeneration and Alzheimer’s disease

Abstract Maintaining cellular homeostasis by removing damaged and senescent mitochondria, a process termed mitophagy, is crucial in preventing Alzheimer’s disease (AD) and represents a promising therapeutic target. Our previous research revealed altered mitophagy biomarkers, such as increased CSF an...

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Bibliographic Details
Main Authors: Kateřina Veverová, Alžběta Katonová, Hana Horáková, Jan Laczó, Francesco Angelucci, Jakub Hort, Sofie Lautrup, Evandro Fei Fang, Martin Vyhnálek
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Acta Neuropathologica Communications
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Online Access:https://doi.org/10.1186/s40478-025-01954-9
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