ROS-responsive death receptor 5 fusion protein nano-delivery system enhances myocardial ischemia-reperfusion injury protection

ROS-responsive death receptor 5 fusion protein nano-delivery system enhances myocardial ischemia-reperfusion injury protection

The microenvironment characterized by inflammation and oxidative stress plays a crucial role in the pathogenesis of myocardial ischemia-reperfusion (I/R) injury. The death receptor 5 fusion protein (sDR5-Fc) specifically targets and blocks the key protein-tumor necrosis factor related apoptosis indu...

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Bibliographic Details
Main Authors: Xiaoyu Liang, Yang Zhang, Changduo Wang, Huiyang Li, Quan Li, Yicong Ye, Chenchen Tu, Xiliang Zhao, Jing Yang, Yong Zeng
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Myocardial ischemia-reperfusion
sDR5-Fc
TRAIL
ROS-Responsive
Anti-apoptotic
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425004594
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