Cancer therapy via neoepitope-specific monoclonal antibody cocktails

Cancer therapy via neoepitope-specific monoclonal antibody cocktails

Abstract Cellular heterogeneity presents a significant challenge to cancer treatment. Antibody therapies targeting individual tumor-associated antigens can be extremely effective but are not suited for all patients and often fail against tumors with heterogeneous expression as tumor cells with low o...

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Bibliographic Details
Main Authors: Colin J. Hartman, Asmaa O. Mohamed, Girja S. Shukla, Stephanie C. Pero, Yu-Jing Sun, Roberto S. Rodríguez-Jimenez, Nicholas F. Genovese, Nico M. Kohler, Thomas R. Hemphill, Yina H. Huang, David N. Krag, Margaret E. Ackerman
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Monoclonal antibody
Neoepitope
Phage display
Yeast display
Melanoma
Effector function
Online Access:https://doi.org/10.1007/s00262-025-04075-3
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