The association of factor VIII activity levels with bleeding and quality of life in haemophilia a: findings from the European CHESS II study

The association of factor VIII activity levels with bleeding and quality of life in haemophilia a: findings from the European CHESS II study

Abstract Background Haemophilia A is a rare disorder leading to excessive bleeding, resulting from a deficiency in circulating clotting factor VIII. While we know that raising factor VIII levels for extended periods of time would reduce the frequency of injections required and provide more consisten...

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Bibliographic Details
Main Authors: Cheryl Jones, Yunchou Wu, Nana Kragh, Linda Bystrická, Amanda Wilson, Tom Burke
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Annual bleeding rate
Factor VIII level
Hemophilia A
Health-related quality of life
Quality of life
Haemophilia
Online Access:https://doi.org/10.1186/s13023-025-03699-z
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