Towards harmonized holmium-166 SPECT image quality for dosimetry: a multi-center, multi-vendor study

Towards harmonized holmium-166 SPECT image quality for dosimetry: a multi-center, multi-vendor study

Abstract Background Reliable dosimetry based on SPECT/CT imaging is essential to achieve personalized 166Ho-radioembolization treatment planning and evaluation. This study quantitatively evaluates multiple acquisition and reconstruction protocols for 166Ho-SPECT imaging based on data from five Dutch...

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Main Authors: Lovisa E. L. Westlund Gotby, Martina Stella, Camille D. E. Van Speybroeck, Daphne Lobeek, Floris H. P. van Velden, Mette K. Stam, Petra Dibbets-Schneider, Daphne M. V. de Vries-Huizing, Erik-Jan Rijkhorst, Berlinda J. de Wit-van de Veen, Roel Wierts, Rob van Rooij
Format: Article
Language:English
Published: SpringerOpen 2025-03-01
Series:EJNMMI Physics
Subjects:
Holmium-166
SPECT/CT
Radioembolization
Phantom study
Image quality
Dual-energy window scatter correction
Online Access:https://doi.org/10.1186/s40658-025-00733-8
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