Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms

This paper reviews the therapeutically beneficial effects of progressive resistance exercise (PRE) on Parkinson's disease (PD). First, this paper discusses the rationale for PRE in PD. Within the first section, the review discusses the central mechanisms that underlie bradykinesia and muscle we...

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Main Authors: Fabian J. David, Miriam R. Rafferty, Julie A. Robichaud, Janey Prodoehl, Wendy M. Kohrt, David E. Vaillancourt, Daniel M. Corcos
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2012/124527
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author Fabian J. David
Miriam R. Rafferty
Julie A. Robichaud
Janey Prodoehl
Wendy M. Kohrt
David E. Vaillancourt
Daniel M. Corcos
author_facet Fabian J. David
Miriam R. Rafferty
Julie A. Robichaud
Janey Prodoehl
Wendy M. Kohrt
David E. Vaillancourt
Daniel M. Corcos
author_sort Fabian J. David
collection DOAJ
description This paper reviews the therapeutically beneficial effects of progressive resistance exercise (PRE) on Parkinson's disease (PD). First, this paper discusses the rationale for PRE in PD. Within the first section, the review discusses the central mechanisms that underlie bradykinesia and muscle weakness, highlights findings related to the central changes that accompany PRE in healthy individuals, and extends these findings to individuals with PD. It then illustrates the hypothesized positive effects of PRE on nigro-striatal-thalamo-cortical activation and connectivity. Second, it reviews recent findings of the use of PRE in individuals with PD. Finally, knowledge gaps of using PRE on individuals with PD are discussed along with suggestions for future research.
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series Parkinson's Disease
spelling doaj-art-8233bc095efd49d5a06369be8bb4a78c2025-08-20T02:08:28ZengWileyParkinson's Disease2090-80832042-00802012-01-01201210.1155/2012/124527124527Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential MechanismsFabian J. David0Miriam R. Rafferty1Julie A. Robichaud2Janey Prodoehl3Wendy M. Kohrt4David E. Vaillancourt5Daniel M. Corcos6Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USAGraduate Program in Neuroscience, University of Illinois at Chicago, Chicago, IL 60612, USADepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USADepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USADivision of Geriatric Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USADepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL 32611, USADepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USAThis paper reviews the therapeutically beneficial effects of progressive resistance exercise (PRE) on Parkinson's disease (PD). First, this paper discusses the rationale for PRE in PD. Within the first section, the review discusses the central mechanisms that underlie bradykinesia and muscle weakness, highlights findings related to the central changes that accompany PRE in healthy individuals, and extends these findings to individuals with PD. It then illustrates the hypothesized positive effects of PRE on nigro-striatal-thalamo-cortical activation and connectivity. Second, it reviews recent findings of the use of PRE in individuals with PD. Finally, knowledge gaps of using PRE on individuals with PD are discussed along with suggestions for future research.http://dx.doi.org/10.1155/2012/124527
spellingShingle Fabian J. David
Miriam R. Rafferty
Julie A. Robichaud
Janey Prodoehl
Wendy M. Kohrt
David E. Vaillancourt
Daniel M. Corcos
Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms
Parkinson's Disease
title Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms
title_full Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms
title_fullStr Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms
title_full_unstemmed Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms
title_short Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms
title_sort progressive resistance exercise and parkinson s disease a review of potential mechanisms
url http://dx.doi.org/10.1155/2012/124527
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