High-dose radiation induces dendritic cells maturation by promoting immunogenic cell death in nasopharyngeal carcinoma

High-dose radiation induces dendritic cells maturation by promoting immunogenic cell death in nasopharyngeal carcinoma

Aim and backgroundDue to the radiosensitivity and deep anatomical location of nasopharyngeal carcinoma (NPC), radiotherapy serves as the cornerstone of standardized treatment for this malignancy. Beyond its cytotoxic effects, radiotherapy can serve as an immunological adjuvant by inducing immunogeni...

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Bibliographic Details
Main Authors: Xianlin Zeng, Xianhuai Jin, Ji Leng, Shuai Zhang, Yun Wang, Jin Chen, Shichao Zhang, Lijing Teng, Zuquan Hu, Shi Zhou, Zhu Zeng, Jinhua Long
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
radiotherapy
nasopharyngeal carcinoma
immune response
immunogenic cell death
dendritic cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1554018/full
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