Posterior Urethral Valves
The most common cause of lower urinary tract obstruction in male infants is posterior urethral valves. Although the incidence has remained stable, the neonatal mortality for this disorder has improved due to early diagnosis and intensive neonatal care, thanks in part to the widespread use of prenata...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2009.127 |
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| author | Steve J. Hodges Bhavin Patel Gordon McLorie Anthony Atala |
| author_facet | Steve J. Hodges Bhavin Patel Gordon McLorie Anthony Atala |
| author_sort | Steve J. Hodges |
| collection | DOAJ |
| description | The most common cause of lower urinary tract obstruction in male infants is posterior urethral valves. Although the incidence has remained stable, the neonatal mortality for this disorder has improved due to early diagnosis and intensive neonatal care, thanks in part to the widespread use of prenatal ultrasound evaluations. In fact, the most common reason for the diagnosis of posterior urethral valves presently is the evaluation of infants for prenatal hydronephrosis. Since these children are often diagnosed early, the urethral obstruction can be alleviated rapidly through catheter insertion and eventual surgery, and their metabolic derangements can be normalized without delay, avoiding preventable infant mortality. Of the children that survive, however, early diagnosis has not had much effect on their long-term prognosis, as 30% still develop renal insufficiency before adolescence. A better understanding of the exact cause of the congenital obstruction of the male posterior urethra, prevention of postnatal bladder and renal injury, and the development of safe methods to treat urethral obstruction prenatally (and thereby avoiding the bladder and renal damage due to obstructive uropathy) are the goals for the care of children with posterior urethral valves[1]. |
| format | Article |
| id | doaj-art-8227a5d0bb5d419e81bb65794bc0eebc |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-8227a5d0bb5d419e81bb65794bc0eebc2025-08-20T03:35:27ZengWileyThe Scientific World Journal1537-744X2009-01-0191119112610.1100/tsw.2009.127Posterior Urethral ValvesSteve J. Hodges0Bhavin Patel1Gordon McLorie2Anthony Atala3Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USADepartment of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USADepartment of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USADepartment of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USAThe most common cause of lower urinary tract obstruction in male infants is posterior urethral valves. Although the incidence has remained stable, the neonatal mortality for this disorder has improved due to early diagnosis and intensive neonatal care, thanks in part to the widespread use of prenatal ultrasound evaluations. In fact, the most common reason for the diagnosis of posterior urethral valves presently is the evaluation of infants for prenatal hydronephrosis. Since these children are often diagnosed early, the urethral obstruction can be alleviated rapidly through catheter insertion and eventual surgery, and their metabolic derangements can be normalized without delay, avoiding preventable infant mortality. Of the children that survive, however, early diagnosis has not had much effect on their long-term prognosis, as 30% still develop renal insufficiency before adolescence. A better understanding of the exact cause of the congenital obstruction of the male posterior urethra, prevention of postnatal bladder and renal injury, and the development of safe methods to treat urethral obstruction prenatally (and thereby avoiding the bladder and renal damage due to obstructive uropathy) are the goals for the care of children with posterior urethral valves[1].http://dx.doi.org/10.1100/tsw.2009.127 |
| spellingShingle | Steve J. Hodges Bhavin Patel Gordon McLorie Anthony Atala Posterior Urethral Valves The Scientific World Journal |
| title | Posterior Urethral Valves |
| title_full | Posterior Urethral Valves |
| title_fullStr | Posterior Urethral Valves |
| title_full_unstemmed | Posterior Urethral Valves |
| title_short | Posterior Urethral Valves |
| title_sort | posterior urethral valves |
| url | http://dx.doi.org/10.1100/tsw.2009.127 |
| work_keys_str_mv | AT stevejhodges posteriorurethralvalves AT bhavinpatel posteriorurethralvalves AT gordonmclorie posteriorurethralvalves AT anthonyatala posteriorurethralvalves |