Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective Therapy

Background. Transanal irrigation (TAI) can successfully treat neurogenic bowel dysfunction (NBD), but patient perception of its use in chronic idiopathic constipation (CIC) is unknown. Objective. To evaluate patient perceptions of the efficacy and safety of TAI for CIC and whether there are predicti...

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Main Authors: Kevin J. Etherson, Ian Minty, Iain M. Bain, Jeremy Cundall, Yan Yiannakou
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2017/3826087
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author Kevin J. Etherson
Ian Minty
Iain M. Bain
Jeremy Cundall
Yan Yiannakou
author_facet Kevin J. Etherson
Ian Minty
Iain M. Bain
Jeremy Cundall
Yan Yiannakou
author_sort Kevin J. Etherson
collection DOAJ
description Background. Transanal irrigation (TAI) can successfully treat neurogenic bowel dysfunction (NBD), but patient perception of its use in chronic idiopathic constipation (CIC) is unknown. Objective. To evaluate patient perceptions of the efficacy and safety of TAI for CIC and whether there are predictive factors of perceived treatment response. Methods. Prospective data collection of baseline physiology and symptom severity; retrospective evaluation of efficacy and safety perceptions using a snapshot survey. All patients fulfilling the Rome III criteria for functional constipation with chronic idiopathic aetiology were included. The main outcome measure was the duration of patients’ usage of TAI. Results. 102 patients reported 21,476 irrigations over 119 patient years, with a mean duration of therapy use of 60.5 weeks [SD 73.2 : SE 7.3]. Overall symptom improvement included general well-being (65%), rectal clearance (63%), bloating (49%), abdominal pain (48%), and bowel frequency (42%). 68 patients (67%) were “moderately better” or “very much better” on a satisfaction question. Reported complications were minor. No correlation was demonstrated between duration of therapy use and baseline measures. Conclusion. A significant proportion of CIC sufferers use TAI as a long-term or bridging therapy and perceive it as safe. This therapy demands a prospective investigation of efficacy and safety.
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spelling doaj-art-8222a11fc84749b5be03b94de0c1b1722025-08-20T02:08:28ZengWileyGastroenterology Research and Practice1687-61211687-630X2017-01-01201710.1155/2017/38260873826087Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective TherapyKevin J. Etherson0Ian Minty1Iain M. Bain2Jeremy Cundall3Yan Yiannakou4Department of Colorectal Surgery, County Durham and Darlington NHS Foundation Trust, Durham, UKDepartment of Radiology, County Durham and Darlington NHS Foundation Trust, Durham, UKDepartment of Colorectal Surgery, County Durham and Darlington NHS Foundation Trust, Durham, UKDepartment of Colorectal Surgery, County Durham and Darlington NHS Foundation Trust, Durham, UKDepartment of Colorectal Surgery, County Durham and Darlington NHS Foundation Trust, Durham, UKBackground. Transanal irrigation (TAI) can successfully treat neurogenic bowel dysfunction (NBD), but patient perception of its use in chronic idiopathic constipation (CIC) is unknown. Objective. To evaluate patient perceptions of the efficacy and safety of TAI for CIC and whether there are predictive factors of perceived treatment response. Methods. Prospective data collection of baseline physiology and symptom severity; retrospective evaluation of efficacy and safety perceptions using a snapshot survey. All patients fulfilling the Rome III criteria for functional constipation with chronic idiopathic aetiology were included. The main outcome measure was the duration of patients’ usage of TAI. Results. 102 patients reported 21,476 irrigations over 119 patient years, with a mean duration of therapy use of 60.5 weeks [SD 73.2 : SE 7.3]. Overall symptom improvement included general well-being (65%), rectal clearance (63%), bloating (49%), abdominal pain (48%), and bowel frequency (42%). 68 patients (67%) were “moderately better” or “very much better” on a satisfaction question. Reported complications were minor. No correlation was demonstrated between duration of therapy use and baseline measures. Conclusion. A significant proportion of CIC sufferers use TAI as a long-term or bridging therapy and perceive it as safe. This therapy demands a prospective investigation of efficacy and safety.http://dx.doi.org/10.1155/2017/3826087
spellingShingle Kevin J. Etherson
Ian Minty
Iain M. Bain
Jeremy Cundall
Yan Yiannakou
Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective Therapy
Gastroenterology Research and Practice
title Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective Therapy
title_full Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective Therapy
title_fullStr Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective Therapy
title_full_unstemmed Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective Therapy
title_short Transanal Irrigation for Refractory Chronic Idiopathic Constipation: Patients Perceive a Safe and Effective Therapy
title_sort transanal irrigation for refractory chronic idiopathic constipation patients perceive a safe and effective therapy
url http://dx.doi.org/10.1155/2017/3826087
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