CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER
The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ,...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/42 |
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| Summary: | The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ, as well as antibodies against TNFα и IFNα. Moreover, we have determined diagnostically significant levels of cytokines and their combinations. On the basis of estimated diagnostic values, one may evaluate both current status of the tumor, as well as its potential malignancy grade. |
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| ISSN: | 1563-0625 2313-741X |