miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure

miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure

Hypertension is not merely a vascular disorder but a significant risk factor for neural impairment. Moreover, healthcare for the hypertensive population with environmental or occupational pollutants has become an issue of increasing concern in public health. As a traditional neurotoxic heavy metal,...

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Bibliographic Details
Main Authors: Yuran Wang, Zeming Wang, Han Hao, Yuwei Zhao, Jian Wang, Weixuan Wang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Toxics
Subjects:
hypertension
Pb exposure
miR-26a-5p
ADAM17
microglia
TREM2
Online Access:https://www.mdpi.com/2305-6304/13/1/37
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