Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance
Objective To investigate different E.coli urinary tract infection germ line genetic typing and drug resistance of relevance.Methods Select our hospital between January 2013 and March2014 separation of 122 strains within 48 h after admission e.coli urinary tract infection and 108 strains after 48 h a...
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Editorial Department of Journal of Clinical Nephrology
2015-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| author | MEI Li-fan WANG Rong-cong JIAO Shi |
| author_facet | MEI Li-fan WANG Rong-cong JIAO Shi |
| author_sort | MEI Li-fan |
| collection | DOAJ |
| description | Objective To investigate different E.coli urinary tract infection germ line genetic typing and drug resistance of relevance.Methods Select our hospital between January 2013 and March2014 separation of 122 strains within 48 h after admission e.coli urinary tract infection and 108 strains after 48 h after admission urinary tract infection e.coli as a clinical research objects,all samples are selected from mid-stream specimen of urine,urinary tract infection patients with isolated within 48 h after admission in patients with urinary tract infection e.coli as a community infected bacteria,isolated after 48 h after admission in patients with urinary tract infection e.coli bacteria for hospital infection,mining API20 E enterobacteriaceae bacteria identification kit with the French company ATB microbial identification of strains,semi-automatic analyzer with producer diffusion method determination of urinary tract infection of e.coli drug sensitivity,contrast different genetic types of tie points urinary tract infections e.coli resistance,produce broad-spectrum beta lactamase(extended spectrum beta lactamases,ESBLs) rate and the distribution of infection in hospital and community infection.Results Among the 230 strains of Escherichia coli,138 strains of producing strains were detected,and 34 strains of ESBLs and AmpC were detected by ESBLs76 and AmpC.230 strains of Escherichia coli to antibiotics resistance:resistance to commonly used antibiotics in clinic from top to bottom in turn:cotrimoxazole 81.7%,piperacillin,pull Westwood 76.7%,74.2% of ampicillin,ampicillin sulbactam 61.7%,butylamine card that mildew element 61.7%,cefuroxime 60.8%,cephalosporins cefpodoxime 59.2%,ammonia aztreonam 59.2%,pethidine pull Xin Lin He cling to Zun 32.5%,cefazolin 68.3%,gentamicin 57.5%,cephalosporins cefotaxime 43.3%,cefotaxime cefepime 38.3%,cefotaxime and 33.3%of cefoxitin,imipenem 0.8%.①According to the test results,and no bacterial infection in the community and hospital infection bacteria are among the highest proportion of D-type germ line genetic typing of community-acquired bacterial infections and hospital bacteria statistically significant difference(P>0.05);② Yield of AmpC,ESBLs and simultaneously producing ESBLs and AmpC enzyme in Escherichia coli antibiotic resistance rates of 14 except imipenem above average.Conclusions Hospital infection with Escherichia coli D-type ESBLs producing Escherichia coli infection in the community of the highest rates of B1-type,D-type E.coli to most highly resistant to antimicrobial drugs. |
| format | Article |
| id | doaj-art-820e9d77961642d6801edaf2ae5b6d1d |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2015-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-820e9d77961642d6801edaf2ae5b6d1d2025-08-20T01:51:12ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902015-01-0156056357920470Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistanceMEI Li-fanWANG Rong-congJIAO ShiObjective To investigate different E.coli urinary tract infection germ line genetic typing and drug resistance of relevance.Methods Select our hospital between January 2013 and March2014 separation of 122 strains within 48 h after admission e.coli urinary tract infection and 108 strains after 48 h after admission urinary tract infection e.coli as a clinical research objects,all samples are selected from mid-stream specimen of urine,urinary tract infection patients with isolated within 48 h after admission in patients with urinary tract infection e.coli as a community infected bacteria,isolated after 48 h after admission in patients with urinary tract infection e.coli bacteria for hospital infection,mining API20 E enterobacteriaceae bacteria identification kit with the French company ATB microbial identification of strains,semi-automatic analyzer with producer diffusion method determination of urinary tract infection of e.coli drug sensitivity,contrast different genetic types of tie points urinary tract infections e.coli resistance,produce broad-spectrum beta lactamase(extended spectrum beta lactamases,ESBLs) rate and the distribution of infection in hospital and community infection.Results Among the 230 strains of Escherichia coli,138 strains of producing strains were detected,and 34 strains of ESBLs and AmpC were detected by ESBLs76 and AmpC.230 strains of Escherichia coli to antibiotics resistance:resistance to commonly used antibiotics in clinic from top to bottom in turn:cotrimoxazole 81.7%,piperacillin,pull Westwood 76.7%,74.2% of ampicillin,ampicillin sulbactam 61.7%,butylamine card that mildew element 61.7%,cefuroxime 60.8%,cephalosporins cefpodoxime 59.2%,ammonia aztreonam 59.2%,pethidine pull Xin Lin He cling to Zun 32.5%,cefazolin 68.3%,gentamicin 57.5%,cephalosporins cefotaxime 43.3%,cefotaxime cefepime 38.3%,cefotaxime and 33.3%of cefoxitin,imipenem 0.8%.①According to the test results,and no bacterial infection in the community and hospital infection bacteria are among the highest proportion of D-type germ line genetic typing of community-acquired bacterial infections and hospital bacteria statistically significant difference(P>0.05);② Yield of AmpC,ESBLs and simultaneously producing ESBLs and AmpC enzyme in Escherichia coli antibiotic resistance rates of 14 except imipenem above average.Conclusions Hospital infection with Escherichia coli D-type ESBLs producing Escherichia coli infection in the community of the highest rates of B1-type,D-type E.coli to most highly resistant to antimicrobial drugs.http://www.lcszb.com/thesisDetails?columnId=57920470&Fpath=home&index=0Urinary tract infectionEscherichia coliDrug resistance |
| spellingShingle | MEI Li-fan WANG Rong-cong JIAO Shi Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance Linchuang shenzangbing zazhi Urinary tract infection Escherichia coli Drug resistance |
| title | Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance |
| title_full | Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance |
| title_fullStr | Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance |
| title_full_unstemmed | Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance |
| title_short | Escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance |
| title_sort | escherichia coli urinary tract infection germ line genetic typing and correlation of drug resistance |
| topic | Urinary tract infection Escherichia coli Drug resistance |
| url | http://www.lcszb.com/thesisDetails?columnId=57920470&Fpath=home&index=0 |
| work_keys_str_mv | AT meilifan escherichiacoliurinarytractinfectiongermlinegenetictypingandcorrelationofdrugresistance AT wangrongcong escherichiacoliurinarytractinfectiongermlinegenetictypingandcorrelationofdrugresistance AT jiaoshi escherichiacoliurinarytractinfectiongermlinegenetictypingandcorrelationofdrugresistance |