Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs

Ovine Pulmonary adenomatosis OPA is a frequent condition that affects small ruminants, characterized by inflammation of the lung parenchyma, and causes polyp-like hyperplasia of the epithelium lining the alveoli and interstitial tissue like bronchi. It is frequently brought on by the Jaagsiekte viru...

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Main Authors: Osama Z. Jiad, Ahmed M. Al-Saidya
Format: Article
Language:Arabic
Published: University of Mosul, College of Veterinary Medicine 2025-01-01
Series:Iraqi Journal of Veterinary Sciences
Subjects:
Online Access:https://www.vetmedmosul.com/article_186015_d99ece2adf84cddbd556ae820f1e73e5.pdf
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author Osama Z. Jiad
Ahmed M. Al-Saidya
author_facet Osama Z. Jiad
Ahmed M. Al-Saidya
author_sort Osama Z. Jiad
collection DOAJ
description Ovine Pulmonary adenomatosis OPA is a frequent condition that affects small ruminants, characterized by inflammation of the lung parenchyma, and causes polyp-like hyperplasia of the epithelium lining the alveoli and interstitial tissue like bronchi. It is frequently brought on by the Jaagsiekte virus. Samples from sheep animals at Mosul's slaughterhouse and butcher shops were collected. The RT-PCR results consider the first molecular identification of the JSRV virus in Mosul city. The Macroscopic examination revealed gray-colored tumor nodules scattered across the surfaces of the lung lobes. The tumor tissue had clear and distinct boundaries from the adjacent pink pneumatic lung. Histological analysis showed nodular tumor areas (proliferative pulmonary nodules) were composed of carcinomatous cells supplementary with an adequate amount of extracellular matrix, characteristic columnar and cuboidal metaplasia, as well as hyperplasia of pulmonary cells, especially the pneumocytes (type II), an epithelial cell (secretory types) in the pulmonary alveoli, Non-ciliated Clara cells as well as the epithelial lining of the terminal bronchioles. Finally, our study sheds light and provides data on the importance of OPA in Mosul abattoir through the PCR diagnosis of the causative agent, and the macroscopic and histological pathological changes.
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institution Kabale University
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2071-1255
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publisher University of Mosul, College of Veterinary Medicine
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series Iraqi Journal of Veterinary Sciences
spelling doaj-art-820e362ebd5b45aca5e838202b4874702025-02-04T13:11:42ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552025-01-01391596410.33899/ijvs.2024.148936.3622186015Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirsOsama Z. Jiad0Ahmed M. Al-Saidya1Veterinarian, Private Sector, Mosul, IraqDepartment of Pathology and Poultry, College of Veterinary Medicine, University of Mosul, Mosul, IraqOvine Pulmonary adenomatosis OPA is a frequent condition that affects small ruminants, characterized by inflammation of the lung parenchyma, and causes polyp-like hyperplasia of the epithelium lining the alveoli and interstitial tissue like bronchi. It is frequently brought on by the Jaagsiekte virus. Samples from sheep animals at Mosul's slaughterhouse and butcher shops were collected. The RT-PCR results consider the first molecular identification of the JSRV virus in Mosul city. The Macroscopic examination revealed gray-colored tumor nodules scattered across the surfaces of the lung lobes. The tumor tissue had clear and distinct boundaries from the adjacent pink pneumatic lung. Histological analysis showed nodular tumor areas (proliferative pulmonary nodules) were composed of carcinomatous cells supplementary with an adequate amount of extracellular matrix, characteristic columnar and cuboidal metaplasia, as well as hyperplasia of pulmonary cells, especially the pneumocytes (type II), an epithelial cell (secretory types) in the pulmonary alveoli, Non-ciliated Clara cells as well as the epithelial lining of the terminal bronchioles. Finally, our study sheds light and provides data on the importance of OPA in Mosul abattoir through the PCR diagnosis of the causative agent, and the macroscopic and histological pathological changes.https://www.vetmedmosul.com/article_186015_d99ece2adf84cddbd556ae820f1e73e5.pdflungpathologypcrsheep
spellingShingle Osama Z. Jiad
Ahmed M. Al-Saidya
Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs
Iraqi Journal of Veterinary Sciences
lung
pathology
pcr
sheep
title Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs
title_full Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs
title_fullStr Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs
title_full_unstemmed Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs
title_short Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs
title_sort molecular and pathological identification of ovine pulmonary adenomatosis at mosul city abattoirs
topic lung
pathology
pcr
sheep
url https://www.vetmedmosul.com/article_186015_d99ece2adf84cddbd556ae820f1e73e5.pdf
work_keys_str_mv AT osamazjiad molecularandpathologicalidentificationofovinepulmonaryadenomatosisatmosulcityabattoirs
AT ahmedmalsaidya molecularandpathologicalidentificationofovinepulmonaryadenomatosisatmosulcityabattoirs