Portal hypertension aggravates Helicobacter pylori induced liver injury in mice via activating pyroptosis pathway

Portal hypertension aggravates Helicobacter pylori induced liver injury in mice via activating pyroptosis pathway

Abstract In recent years, it has been discovered that the pathogenic effect of Helicobacter pylori (H. pylori) is not only limited to the gastroduodenal region, but also plays a certain role in the occurrence and development of liver diseases. The aim of this study is to ascertain the existence of H...

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Bibliographic Details
Main Authors: JiKe Hu, Lei Gao, Ewetse Paul Maswikiti, Xuemei Li, Baohong Gu, Yang Yu, Haiyuan Li, Hao Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Helicobacter pylori
Portal hypertension
Pyroptosis
NLRP3
Liver injury
Online Access:https://doi.org/10.1038/s41598-025-96132-1
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