FKBP10 expression and TP53 mutation predict prognosis and chemotherapy response in triple-negative breast cancer

FKBP10 expression and TP53 mutation predict prognosis and chemotherapy response in triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) lacks targeted therapies. FKBP10 contributes to oncogenesis and chemoresistance. We investigated FKBP10’s prognostic value in TNBC. Methods We retrospectively analyzed 190 TNBC patients receiving neoadjuvant chemotherapy. Patients were stratif...

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Bibliographic Details
Main Authors: Yan Li, Chi Zhang, Jian Chen, Gang Tu, Lingfeng Tang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Neoadjuvant chemotherapy
Breast cancer
FKBP10
TP53
Prognosis
Online Access:https://doi.org/10.1007/s12672-025-03275-8
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