The fecal metabolome and microbiome are altered in dogs with idiopathic epilepsy compared to healthy dogs

The fecal metabolome and microbiome are altered in dogs with idiopathic epilepsy compared to healthy dogs

Abstract Idiopathic epilepsy (IE) is the most common chronic neurological disease in dogs, and a natural animal model for human epilepsy types with genetic and unknown etiology. The microbiota-gut-brain axis (MGBA) is a promising target for improving brain health in individuals where brain function...

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Bibliographic Details
Main Authors: Fien Verdoodt, Myriam Hesta, Evy Goossens, Filip Van Immerseel, Jenifer Molina, Luc Van Ham, Lynn Vanhaecke, Lieselot Y. Hemeryck, Sofie F.M. Bhatti
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Epilepsy
Gut-Brain-Axis
Metabolomics
Microbiome
Canine
Online Access:https://doi.org/10.1038/s41598-025-09919-7
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