m6A Modulates RAN Translation From CAG Repeat Expansion RNA

m6A Modulates RAN Translation From CAG Repeat Expansion RNA

ABSTRACT Nucleotide repeat expansions contribute to the development of a number of neurodegenerative diseases. Recent studies revealed that DNA sequences with CAG and other nucleotide repeat expansions can undergo bidirectional transcription, and the ensuing transcripts could be translated into prot...

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Bibliographic Details
Main Authors: Yuxiang Sun, Zhouxian Li, Hui Dai, Yinsheng Wang
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Aggregate
Subjects:
CAG repeat expansion
N6‐methyladenosine
RAN translation
Online Access:https://doi.org/10.1002/agt2.70072
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