INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALS

The aim of research – to study and compare the cells’ structure of infiltration around polypropylene material in different time and to compare the results of immunohistochemical parameters in around implant and intact tissue of experimental animals in 12 months after implantation. Material and meth...

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Main Authors: Игорь Александрович Эйзенах, Максим Александрович Бакарев, Галина Анатольевна Лапий, Вадим Гельевич Мозес, Кира Борисовна Мозес
Format: Article
Language:Russian
Published: The Publishing House Medicine and Enlightenment 2020-09-01
Series:Медицина в Кузбассе
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Online Access:https://mednauki.ru/index.php/MK/article/view/489
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author Игорь Александрович Эйзенах
Максим Александрович Бакарев
Галина Анатольевна Лапий
Вадим Гельевич Мозес
Кира Борисовна Мозес
author_facet Игорь Александрович Эйзенах
Максим Александрович Бакарев
Галина Анатольевна Лапий
Вадим Гельевич Мозес
Кира Борисовна Мозес
author_sort Игорь Александрович Эйзенах
collection DOAJ
description The aim of research – to study and compare the cells’ structure of infiltration around polypropylene material in different time and to compare the results of immunohistochemical parameters in around implant and intact tissue of experimental animals in 12 months after implantation. Material and methods. It have been done morphometry in 14 days, 1, 2, 3, 6, 9, 12 months and immunohistochemical examination markers CD3, CD8, CD20, CD38, CD68 in 12 months the tissue around polypropylene material after implantation by 35 laboratory rats. Conclusion. Regardless of polypropylene’s bioinertness, the implantation this material causes inflammation in tissue, which persists in 12 months in lymphocytes and leucocytes reaction and the plasma cells’ high level, response for induction stage of humoral immunity.
format Article
id doaj-art-81fe1bccf76e489b9ce6225bee25869c
institution Kabale University
issn 1819-0901
2588-0411
language Russian
publishDate 2020-09-01
publisher The Publishing House Medicine and Enlightenment
record_format Article
series Медицина в Кузбассе
spelling doaj-art-81fe1bccf76e489b9ce6225bee25869c2025-08-20T03:34:02ZrusThe Publishing House Medicine and EnlightenmentМедицина в Кузбассе1819-09012588-04112020-09-011933541437INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALSИгорь Александрович Эйзенах0Максим Александрович Бакарев1Галина Анатольевна Лапий2Вадим Гельевич Мозес3Кира Борисовна Мозес4ФГБНУ ФИЦ ФТМ, г. НовосибирскФГБНУ ФИЦ ФТМ, г. НовосибирскФГБНУ ФИЦ ФТМ, г. НовосибирскФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоThe aim of research – to study and compare the cells’ structure of infiltration around polypropylene material in different time and to compare the results of immunohistochemical parameters in around implant and intact tissue of experimental animals in 12 months after implantation. Material and methods. It have been done morphometry in 14 days, 1, 2, 3, 6, 9, 12 months and immunohistochemical examination markers CD3, CD8, CD20, CD38, CD68 in 12 months the tissue around polypropylene material after implantation by 35 laboratory rats. Conclusion. Regardless of polypropylene’s bioinertness, the implantation this material causes inflammation in tissue, which persists in 12 months in lymphocytes and leucocytes reaction and the plasma cells’ high level, response for induction stage of humoral immunity.https://mednauki.ru/index.php/MK/article/view/489имплантацияполипропиленвоспаление
spellingShingle Игорь Александрович Эйзенах
Максим Александрович Бакарев
Галина Анатольевна Лапий
Вадим Гельевич Мозес
Кира Борисовна Мозес
INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALS
Медицина в Кузбассе
имплантация
полипропилен
воспаление
title INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALS
title_full INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALS
title_fullStr INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALS
title_full_unstemmed INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALS
title_short INFLAMMATORY AND IMMUNOLOGICAL ASPECTS OF TISSUE REACTION BY POLYPROPYLENE IMPLANTS IN EXPERIMENT WITH ANIMALS
title_sort inflammatory and immunological aspects of tissue reaction by polypropylene implants in experiment with animals
topic имплантация
полипропилен
воспаление
url https://mednauki.ru/index.php/MK/article/view/489
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AT maksimaleksandrovičbakarev inflammatoryandimmunologicalaspectsoftissuereactionbypolypropyleneimplantsinexperimentwithanimals
AT galinaanatolʹevnalapij inflammatoryandimmunologicalaspectsoftissuereactionbypolypropyleneimplantsinexperimentwithanimals
AT vadimgelʹevičmozes inflammatoryandimmunologicalaspectsoftissuereactionbypolypropyleneimplantsinexperimentwithanimals
AT kiraborisovnamozes inflammatoryandimmunologicalaspectsoftissuereactionbypolypropyleneimplantsinexperimentwithanimals