A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial Standards

Objective: To analyze the similarity between Mongolian medicine prescriptions included in the 2020 edition of the Pharmacopoeia of the People’s Republic of China (hereinafter referred to as the Chinese Pharmacopoeia) and Tibetan medicinal compounds according to the Drug Standards of the Ministry of...

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Main Authors: Ji Zang, Cai Rang-Zhou Tai, Jie-Jia Nan, Cai Rang-Nanjia
Format: Article
Language:English
Published: World Scientific Publishing 2024-01-01
Series:Traditional Medicine and Modern Medicine
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Online Access:https://www.worldscientific.com/doi/10.1142/S2575900024500034
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author Ji Zang
Cai Rang-Zhou Tai
Jie-Jia Nan
Cai Rang-Nanjia
author_facet Ji Zang
Cai Rang-Zhou Tai
Jie-Jia Nan
Cai Rang-Nanjia
author_sort Ji Zang
collection DOAJ
description Objective: To analyze the similarity between Mongolian medicine prescriptions included in the 2020 edition of the Pharmacopoeia of the People’s Republic of China (hereinafter referred to as the Chinese Pharmacopoeia) and Tibetan medicinal compounds according to the Drug Standards of the Ministry of Public Health of the People’s Republic of China: Tibetan Medicine (Volume I) (hereinafter referred to as the Ministerial Standards). Methods: A comparative analysis was conducted between Mongolian medicine prescriptions contained in the Chinese Pharmacopoeia and the corresponding Tibetan medicinal compounds included in the Ministerial Standards using Jaccard similarity coefficients and Hellinger distance algorithms across three dimensions: composition, shared drug dosage ratio, and efficacy. Different weights were applied to calculate the comprehensive similarity between the formulas. Simultaneously, we collated and verified the original source literature, and determined the era of composition for each formula. Results: The overall similarity between the Mongolian medicine prescriptions from the Chinese Pharmacopoeia and the Tibetan medicinal compounds from the Ministerial Standards was over 50%. Notably, the composite similarity for the pairings Sanwei Jili San and Sanwei Jili Tangsan, as well as Wuwei Qingzhuo San and Shiliu Anzhi Jinghua San, exceeded 90%. Additionally, six sets of formulas achieved a similarity of over 75%. Literature research has revealed that all 13 sets of formulas first appeared in Tibetan medical literature and were long-standing practices in Tibetan medicine clinics, significantly predating their initial documentation in Mongolian medical literature. Conclusion: The 13 sets of Mongolian medicine prescriptions originated from Tibetan medicinal compounds. Throughout their evolution, the sets adhered to the principles of similar origins and/or properties and effects, leading to the emergence of both commonly used and alternative items. Nevertheless, the efficacy of the formulas has remained highly consistent. The phenomenon of ingredient substitution in the formulas could be attributed to various factors, such as resource availability and cognitive differences among inheritance schools. This study has important implications for further comparative research on content quantification and pharmacological activity. Such research could uncover new medicinal varieties, fostering the sustainable development of Tibetan and Mongolian medicine.
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spelling doaj-art-81f8768ca3df4297acd20cf5ebd7d7d62025-08-20T02:34:35ZengWorld Scientific PublishingTraditional Medicine and Modern Medicine2575-90002575-90192024-01-0107415210.1142/S2575900024500034A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial StandardsJi Zang0Cai Rang-Zhou Tai1Jie-Jia Nan2Cai Rang-Nanjia3College of Pharmacy, Qinghai University for Nationalities, Xining 810000, P. R. ChinaCollege of Pharmacy, Qinghai University for Nationalities, Xining 810000, P. R. ChinaCollege of Pharmacy, Qinghai University for Nationalities, Xining 810000, P. R. ChinaCollege of Pharmacy, Qinghai University for Nationalities, Xining 810000, P. R. ChinaObjective: To analyze the similarity between Mongolian medicine prescriptions included in the 2020 edition of the Pharmacopoeia of the People’s Republic of China (hereinafter referred to as the Chinese Pharmacopoeia) and Tibetan medicinal compounds according to the Drug Standards of the Ministry of Public Health of the People’s Republic of China: Tibetan Medicine (Volume I) (hereinafter referred to as the Ministerial Standards). Methods: A comparative analysis was conducted between Mongolian medicine prescriptions contained in the Chinese Pharmacopoeia and the corresponding Tibetan medicinal compounds included in the Ministerial Standards using Jaccard similarity coefficients and Hellinger distance algorithms across three dimensions: composition, shared drug dosage ratio, and efficacy. Different weights were applied to calculate the comprehensive similarity between the formulas. Simultaneously, we collated and verified the original source literature, and determined the era of composition for each formula. Results: The overall similarity between the Mongolian medicine prescriptions from the Chinese Pharmacopoeia and the Tibetan medicinal compounds from the Ministerial Standards was over 50%. Notably, the composite similarity for the pairings Sanwei Jili San and Sanwei Jili Tangsan, as well as Wuwei Qingzhuo San and Shiliu Anzhi Jinghua San, exceeded 90%. Additionally, six sets of formulas achieved a similarity of over 75%. Literature research has revealed that all 13 sets of formulas first appeared in Tibetan medical literature and were long-standing practices in Tibetan medicine clinics, significantly predating their initial documentation in Mongolian medical literature. Conclusion: The 13 sets of Mongolian medicine prescriptions originated from Tibetan medicinal compounds. Throughout their evolution, the sets adhered to the principles of similar origins and/or properties and effects, leading to the emergence of both commonly used and alternative items. Nevertheless, the efficacy of the formulas has remained highly consistent. The phenomenon of ingredient substitution in the formulas could be attributed to various factors, such as resource availability and cognitive differences among inheritance schools. This study has important implications for further comparative research on content quantification and pharmacological activity. Such research could uncover new medicinal varieties, fostering the sustainable development of Tibetan and Mongolian medicine.https://www.worldscientific.com/doi/10.1142/S2575900024500034Mongolian medicine prescriptionsTibetan medicinal compoundsformula similarity
spellingShingle Ji Zang
Cai Rang-Zhou Tai
Jie-Jia Nan
Cai Rang-Nanjia
A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial Standards
Traditional Medicine and Modern Medicine
Mongolian medicine prescriptions
Tibetan medicinal compounds
formula similarity
title A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial Standards
title_full A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial Standards
title_fullStr A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial Standards
title_full_unstemmed A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial Standards
title_short A comparative study of Mongolian medicine prescriptions in the Chinese Pharmacopoeia and Tibetan medicinal compounds in the Ministerial Standards
title_sort comparative study of mongolian medicine prescriptions in the chinese pharmacopoeia and tibetan medicinal compounds in the ministerial standards
topic Mongolian medicine prescriptions
Tibetan medicinal compounds
formula similarity
url https://www.worldscientific.com/doi/10.1142/S2575900024500034
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