Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic Challenge

Primary cholangiocarcinoma is a rare bile duct epithelial neoplasm that can present with atypical clinical manifestations, complicating its diagnosis. A 62-year-old male showed symptoms suggestive of a complicated hepatic cyst that was later identified as intrahepatic cholangiocarcinoma. The patient...

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Main Authors: Chang Won Ha, Sang Deok Shin, Myung Ji Goh, Byeong Geun Song, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee
Format: Article
Language:English
Published: Jin Publishing & Printing Co. 2025-01-01
Series:The Korean Journal of Gastroenterology
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Online Access:https://www.kjg.or.kr/journal/view.html?uid=6084&vmd=Full
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author Chang Won Ha
Sang Deok Shin
Myung Ji Goh
Byeong Geun Song
Wonseok Kang
Dong Hyun Sinn
Geum-Youn Gwak
Yong-Han Paik
Moon Seok Choi
Joon Hyeok Lee
author_facet Chang Won Ha
Sang Deok Shin
Myung Ji Goh
Byeong Geun Song
Wonseok Kang
Dong Hyun Sinn
Geum-Youn Gwak
Yong-Han Paik
Moon Seok Choi
Joon Hyeok Lee
author_sort Chang Won Ha
collection DOAJ
description Primary cholangiocarcinoma is a rare bile duct epithelial neoplasm that can present with atypical clinical manifestations, complicating its diagnosis. A 62-year-old male showed symptoms suggestive of a complicated hepatic cyst that was later identified as intrahepatic cholangiocarcinoma. The patient presented with abdominal discomfort without fever. Imaging revealed a large cystic lesion in the liver. Despite the initial treatment for a presumed abscess, a biopsy confirmed cholangiocarcinoma. This case highlights the diagnostic challenge of distinguishing between benign complicated hepatic cysts and malignancies, particularly when typical markers of infection are absent. Early biopsy and vigilant assessments are crucial in such presentations to avoid a delayed diagnosis and initiate appropriate treatment.
format Article
id doaj-art-81eecbb3fb494a309e698f9abf20f129
institution Kabale University
issn 1598-9992
2233-6869
language English
publishDate 2025-01-01
publisher Jin Publishing & Printing Co.
record_format Article
series The Korean Journal of Gastroenterology
spelling doaj-art-81eecbb3fb494a309e698f9abf20f1292025-02-07T06:53:57ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692025-01-01851858810.4166/kjg.2024.131Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic ChallengeChang Won Ha0Sang Deok Shin1Myung Ji Goh2Byeong Geun Song3https://orcid.org/0000-0001-9418-7846Wonseok Kang4Dong Hyun Sinn5Geum-Youn Gwak6Yong-Han Paik7Moon Seok Choi8Joon Hyeok Lee9Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaPrimary cholangiocarcinoma is a rare bile duct epithelial neoplasm that can present with atypical clinical manifestations, complicating its diagnosis. A 62-year-old male showed symptoms suggestive of a complicated hepatic cyst that was later identified as intrahepatic cholangiocarcinoma. The patient presented with abdominal discomfort without fever. Imaging revealed a large cystic lesion in the liver. Despite the initial treatment for a presumed abscess, a biopsy confirmed cholangiocarcinoma. This case highlights the diagnostic challenge of distinguishing between benign complicated hepatic cysts and malignancies, particularly when typical markers of infection are absent. Early biopsy and vigilant assessments are crucial in such presentations to avoid a delayed diagnosis and initiate appropriate treatment.https://www.kjg.or.kr/journal/view.html?uid=6084&vmd=Fullliver cystcholangiocarcinomaintrahepatic
spellingShingle Chang Won Ha
Sang Deok Shin
Myung Ji Goh
Byeong Geun Song
Wonseok Kang
Dong Hyun Sinn
Geum-Youn Gwak
Yong-Han Paik
Moon Seok Choi
Joon Hyeok Lee
Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic Challenge
The Korean Journal of Gastroenterology
liver cyst
cholangiocarcinoma
intrahepatic
title Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic Challenge
title_full Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic Challenge
title_fullStr Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic Challenge
title_full_unstemmed Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic Challenge
title_short Primary Cholangiocarcinoma of the Liver Presenting as a Complicated Hepatic Cyst: A Diagnostic Challenge
title_sort primary cholangiocarcinoma of the liver presenting as a complicated hepatic cyst a diagnostic challenge
topic liver cyst
cholangiocarcinoma
intrahepatic
url https://www.kjg.or.kr/journal/view.html?uid=6084&vmd=Full
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