Hearing analysis in heterozygous and homozygous klotho gene deficient mice
Objective: To understand the crucial role of the klotho gene in hearing development in mouse models. Methods: PCR was used to identify CBA mice with different genotypes, i.e. WT, heterozygous (klotho +/−) or homozygous (klotho −/−). Mice phenotype and weight were recorded postnatal 25 days (P-25) an...
Saved in:
| Main Authors: | Na Yuan, Shiwei Qiu, Qian Wang, Wei Zhuang, Guoping Li, Tiantian Sun, Shiming Yang, Yuehua Qiao, Xi Shi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2018-12-01
|
| Series: | Journal of Otology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1672293018300102 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Beyond the homozygous paradigm: symptomatic partial biotinidase deficiency in a heterozygous child—first case report from Nepal
by: Jagdish Kunwar, et al.
Published: (2025-06-01) -
Assessment of CDKN2A homozygous and heterozygous deletions in gliomas across multiple detection platforms
by: Hainan Li, et al.
Published: (2025-06-01) -
Comparative Analysis of Virulence Factors of Homozygous and Heterozygous Strains of Candida albicans Vaginal Isolates
by: Hasti Nouraei, et al.
Published: (2020-01-01) -
Heterozygous interferon signaling deficient mice as animal models for Chikungunya virus infection in the heart
by: Shazeed-Ul Karim, et al.
Published: (2025-05-01) -
Fluctuating hearing loss associated with a novel heterozygous variant in the TNC gene related to nonsyndromic hearing loss
by: Mariana Carolina Castellanos-Acevedo, et al.
Published: (2025-07-01)