Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia
ABSTRACT Little is known about pregnancies and placental changes in women with glycogen storage disease type Ia (GSD Ia). We report on two primipara with GSD Ia who both developed preeclampsia and whose newborns were small for gestational age. Both placentas showed sonomorphological and macroscopica...
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| Format: | Article |
| Language: | English |
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Wiley
2025-07-01
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| Series: | JIMD Reports |
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| Online Access: | https://doi.org/10.1002/jmd2.70025 |
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| author | V. Laufs A. Hasenburg M. A. Busch F. Lang D. Macchiella E. Mildenberger L. Seidmann J. B. Hennermann |
| author_facet | V. Laufs A. Hasenburg M. A. Busch F. Lang D. Macchiella E. Mildenberger L. Seidmann J. B. Hennermann |
| author_sort | V. Laufs |
| collection | DOAJ |
| description | ABSTRACT Little is known about pregnancies and placental changes in women with glycogen storage disease type Ia (GSD Ia). We report on two primipara with GSD Ia who both developed preeclampsia and whose newborns were small for gestational age. Both placentas showed sonomorphological and macroscopical abnormalities. Disease‐specific histological features could not be identified, which should prompt further research. |
| format | Article |
| id | doaj-art-81e4c6096d4f4040a818eef01d175be3 |
| institution | DOAJ |
| issn | 2192-8312 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | JIMD Reports |
| spelling | doaj-art-81e4c6096d4f4040a818eef01d175be32025-08-20T03:08:40ZengWileyJIMD Reports2192-83122025-07-01664n/an/a10.1002/jmd2.70025Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and PreeclampsiaV. Laufs0A. Hasenburg1M. A. Busch2F. Lang3D. Macchiella4E. Mildenberger5L. Seidmann6J. B. Hennermann7Clinic for Obstetrics and Women's Health University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyClinic for Obstetrics and Women's Health University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDivision of Neonatology Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyVilla Metabolica Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyClinic for Obstetrics and Women's Health University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDivision of Neonatology Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyInstitute of Pathology University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyVilla Metabolica Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyABSTRACT Little is known about pregnancies and placental changes in women with glycogen storage disease type Ia (GSD Ia). We report on two primipara with GSD Ia who both developed preeclampsia and whose newborns were small for gestational age. Both placentas showed sonomorphological and macroscopical abnormalities. Disease‐specific histological features could not be identified, which should prompt further research.https://doi.org/10.1002/jmd2.70025carbohydrate storage disorderfetal growth restrictionGSD Iahistologic featuresinherited metabolic diseaseplacenta abnormalities |
| spellingShingle | V. Laufs A. Hasenburg M. A. Busch F. Lang D. Macchiella E. Mildenberger L. Seidmann J. B. Hennermann Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia JIMD Reports carbohydrate storage disorder fetal growth restriction GSD Ia histologic features inherited metabolic disease placenta abnormalities |
| title | Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia |
| title_full | Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia |
| title_fullStr | Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia |
| title_full_unstemmed | Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia |
| title_short | Placenta Pathologies in Two Patients With Glycogen Storage Disease Type Ia and Preeclampsia |
| title_sort | placenta pathologies in two patients with glycogen storage disease type ia and preeclampsia |
| topic | carbohydrate storage disorder fetal growth restriction GSD Ia histologic features inherited metabolic disease placenta abnormalities |
| url | https://doi.org/10.1002/jmd2.70025 |
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