Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover.

Regulation of transforming growth factor-beta (TGF-beta) signaling is critical in vertebrate development, as several members of the TGF-beta family have been shown to act as morphogens, controlling a variety of cell fate decisions depending on concentration. Little is known about the role of intrace...

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Bibliographic Details
Main Authors: Konstantinos J Mavrakis, Rebecca L Andrew, Kian Leong Lee, Chariklia Petropoulou, James E Dixon, Naveenan Navaratnam, Dominic P Norris, Vasso Episkopou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0050067&type=printable
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