Harnessing ferroptosis for precision oncology: challenges and prospects

Abstract The discovery of diverse molecular mechanisms of regulated cell death has opened new avenues for cancer therapy. Ferroptosis, a unique form of cell death driven by iron-catalyzed peroxidation of membrane phospholipids, holds particular promise for targeting resistant cancer types. This revi...

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Bibliographic Details
Main Authors: Roberto Fernández-Acosta, Iuliana Vintea, Ine Koeken, Behrouz Hassannia, Tom Vanden Berghe
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-025-02154-6
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