Demodicosis Cutis and Metabolic Disturbances
Cutaneous demodicosis (CD) is a pilosebaceous unit disease, overlapping clinically with other facial dermatoses, mainly rosacea, and acne. It is usually improved by acaricidal monotherapy. This study investigates the association of CD with metabolic disturbances. It was conducted with 141 patients w...
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| Language: | English |
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Medical University - Pleven
2022-06-01
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| Series: | Journal of Biomedical & Clinical Research |
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| Online Access: | https://jbcr.arphahub.com/article/34618/download/pdf/ |
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| author | Evgeni Hristozov Katya Peeva Valeri Malev Ivelina Yordanova Grisha Mateev |
| author_facet | Evgeni Hristozov Katya Peeva Valeri Malev Ivelina Yordanova Grisha Mateev |
| author_sort | Evgeni Hristozov |
| collection | DOAJ |
| description | Cutaneous demodicosis (CD) is a pilosebaceous unit disease, overlapping clinically with other facial dermatoses, mainly rosacea, and acne. It is usually improved by acaricidal monotherapy. This study investigates the association of CD with metabolic disturbances. It was conducted with 141 patients with primary and secondary CD. The study investigated the correlation between CD and dyslipidemia based on disturbances in total cholesterol (TC) and Low-Density Lipoproteins (LDL) and between CD and impaired glucose tolerance, diagnosed with elevated fasting blood sugar levels, 120 minutes blood sugar levels in oral glucose tolerance test (OGTT) and the mathematically calculated Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index. The study results were verified with control groups. It was established that patients with CD do not show statistically significant deviations in serum lipoproteins compared with the control group. However, the patients with CD tended to have impaired glucose tolerance, demonstrated with elevated fasting glucose levels and elevated HOMA-IR, compared to the control group. Interestingly enough, the tendency towards prediabetes and diabetes was not confirmed by the 120 minutes blood glucose levels of the OGTT. The presented data confirm the need for testing impaired glucose tolerance in every patient with cutaneous demodicosis. Based on the presented evidence, it is recommended to perform the screening by evaluating fasting glucose levels and fasting insulin levels, followed by calculating the HOMA-IR index. |
| format | Article |
| id | doaj-art-81bcf0a2f68643e3a971bb2e6bb3d6bd |
| institution | Kabale University |
| issn | 1313-9053 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Medical University - Pleven |
| record_format | Article |
| series | Journal of Biomedical & Clinical Research |
| spelling | doaj-art-81bcf0a2f68643e3a971bb2e6bb3d6bd2025-08-20T03:36:18ZengMedical University - PlevenJournal of Biomedical & Clinical Research1313-90532022-06-01151475710.2478/jbcr-2022-000634618Demodicosis Cutis and Metabolic DisturbancesEvgeni HristozovKatya PeevaValeri MalevIvelina YordanovaGrisha MateevCutaneous demodicosis (CD) is a pilosebaceous unit disease, overlapping clinically with other facial dermatoses, mainly rosacea, and acne. It is usually improved by acaricidal monotherapy. This study investigates the association of CD with metabolic disturbances. It was conducted with 141 patients with primary and secondary CD. The study investigated the correlation between CD and dyslipidemia based on disturbances in total cholesterol (TC) and Low-Density Lipoproteins (LDL) and between CD and impaired glucose tolerance, diagnosed with elevated fasting blood sugar levels, 120 minutes blood sugar levels in oral glucose tolerance test (OGTT) and the mathematically calculated Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index. The study results were verified with control groups. It was established that patients with CD do not show statistically significant deviations in serum lipoproteins compared with the control group. However, the patients with CD tended to have impaired glucose tolerance, demonstrated with elevated fasting glucose levels and elevated HOMA-IR, compared to the control group. Interestingly enough, the tendency towards prediabetes and diabetes was not confirmed by the 120 minutes blood glucose levels of the OGTT. The presented data confirm the need for testing impaired glucose tolerance in every patient with cutaneous demodicosis. Based on the presented evidence, it is recommended to perform the screening by evaluating fasting glucose levels and fasting insulin levels, followed by calculating the HOMA-IR index.https://jbcr.arphahub.com/article/34618/download/pdf/cutaneous demodicosisrosaceadyslipidemiapred |
| spellingShingle | Evgeni Hristozov Katya Peeva Valeri Malev Ivelina Yordanova Grisha Mateev Demodicosis Cutis and Metabolic Disturbances Journal of Biomedical & Clinical Research cutaneous demodicosis rosacea dyslipidemia pred |
| title | Demodicosis Cutis and Metabolic Disturbances |
| title_full | Demodicosis Cutis and Metabolic Disturbances |
| title_fullStr | Demodicosis Cutis and Metabolic Disturbances |
| title_full_unstemmed | Demodicosis Cutis and Metabolic Disturbances |
| title_short | Demodicosis Cutis and Metabolic Disturbances |
| title_sort | demodicosis cutis and metabolic disturbances |
| topic | cutaneous demodicosis rosacea dyslipidemia pred |
| url | https://jbcr.arphahub.com/article/34618/download/pdf/ |
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