Editorial: Exploring small molecule inhibitors in cardiovascular and cerebrovascular diseases

Editorial: Exploring small molecule inhibitors in cardiovascular and cerebrovascular diseases

Saved in:

Bibliographic Details
Main Authors:	Basveshwar Gawali, Shweta Shrivastava, R. Uday Kumar, Satyendra Kumar Rajput, Manish Kumar Jeengar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Pharmacology
Subjects:	small molecule inhibitors cardiovascular diseases PDE4 inhibitors NLRP3 inflammasome non-invasive biomarkers intracranial aneurysms
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1559488/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Small molecule inhibitors targeting the cancers
by: Gui‐Hong Liu, et al.
Published: (2022-12-01)

Pulmonary fibrosis through the prism of NLRP3 inflammasome: mechanistic pathways and prospective therapeutic innovations
by: Mengxue Wang, et al.
Published: (2025-05-01)

Understanding the Role of NLRP3 Inflammasome in Acute Pancreatitis
by: Konstantinos Papantoniou, et al.
Published: (2024-11-01)

Osteoarthritis: modern aspects of pathogenesis, focus on low-intensity inflammation
by: I. S. Svintsitskaya, et al.
Published: (2025-04-01)

Efficacy and safety of small molecule drugs in the treatment of pityriasis rubra pilaris—A systematic review
by: Xiaofang Zhang, et al.
Published: (2025-02-01)

NLRP3 Inflammasome-Mediated Osteoarthritis: The Role of Epigenetics
by: Yuzhou Liu, et al.
Published: (2025-01-01)

Cardiotoxicity of small-molecule kinase inhibitors in cancer therapy
by: Shuangli Zhu, et al.
Published: (2025-05-01)

PDE Inhibitors and Autophagy Regulators Modulate CRE-Dependent Luciferase Activity in Neuronal Cells from the Mouse Suprachiasmatic Nucleus
by: Erik Maronde, et al.
Published: (2025-08-01)

Phosphodiesterase type 5 inhibitors and erectile dysfunction
by: Catherine Whittaker
Published: (2010-06-01)

Research progress on phosphodiesterase 4 inhibitors in the treatment of palmoplantar pustulosis
by: YAO Xinyi, et al.
Published: (2024-11-01)

Phosphodiesterase Type 5 Inhibitors in Male Reproduction: Molecular Mechanisms and Clinical Implications for Fertility Management
by: Aris Kaltsas, et al.
Published: (2025-01-01)

RETRACTED ARTICLE: Emerging insights into the role of IL-1 inhibitors and colchicine for inflammation control in type 2 diabetes
by: Jianbin Guan, et al.
Published: (2024-06-01)

Membrane-Mediated Action of Phosphodiesterase 5 Inhibitors
by: Anna I. Malykhina, et al.
Published: (2025-04-01)

The effect of colchicine on mortality outcome and duration of hospital stay in patients with COVID‐19: A meta‐analysis of randomized trials
by: Chia Siang Kow, et al.
Published: (2022-02-01)

Editorial: Exploring novel approaches to small molecule kinase inhibitors in cancer treatment
by: Anna Carbone, et al.
Published: (2025-02-01)

Rho-Associated Kinase Inhibitor Fasudil Protects from Sepsis-Induced Acute Kidney Injury in Rat via Suppressing STAT-3 and NLRP-3 Pathway
by: Neslihan Şahin, et al.
Published: (2025-05-01)

Negative Immune Checkpoint Inhibitors
by: Magda Drewniak-Świtalska, et al.
Published: (2025-05-01)

NLRP12-associated periodic syndrome: A description of the authors' own observation and an analysis of literature data
by: M. F. Dubko, et al.
Published: (2017-04-01)

NLRP3 Inflammasome — a new universal target of asymptomatic hyperuricemia and gout management
by: P. A. Lebedev, et al.
Published: (2024-07-01)

The multifaceted role of phosphodiesterase 4 in tumor: from tumorigenesis to immunotherapy
by: Huili-li Ren, et al.
Published: (2025-03-01)

Inhibition of Activated Coagulation Factor XII by the Phosphodiesterase-4 Inhibitor Roflumilast: In Vitro and In Silico Studies
by: Hassan A. Madkhali, et al.
Published: (2025-05-01)

Machine learning aids in the discovery of efficient corrosion inhibitor molecules
by: Haiyan GONG, et al.
Published: (2025-06-01)

Statin versus no statin after treatment with pipeline embolization device for intracranial aneurysms: a meta-analysis
by: Nathalia Soares Barbosa, et al.
Published: (2025-06-01)

Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria
by: Alvaro González‐Dominguez, et al.
Published: (2021-08-01)

Therapeutic effects of mirodenafil, a phosphodiesterase 5 inhibitor, on stroke models in rats
by: Fred Kim, et al.
Published: (2025-01-01)

Ovarian cancer and the heart: pathophysiology, chemotherapy-induced cardiotoxicity, and new therapeutic strategies
by: Megha Nair, et al.
Published: (2025-04-01)

Effect of Tadalafil on cardiac function and left ventricular dimensions in Duchenne muscular dystrophy: safety and cardiac MRI substudy results from a randomized, placebo-controlled trial
by: David Cox, et al.
Published: (2025-04-01)

NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteria
by: Mateusz Szczerba, et al.
Published: (2025-05-01)

Phosphodiesterase 10A as a Therapeutic Target in Neuropsychopharmacology: A Review
by: A. R. Dorotenko, et al.
Published: (2025-05-01)

Targeting DDX3 with a small molecule inhibitor for lung cancer therapy
by: Guus M Bol, et al.
Published: (2015-03-01)

Protective effect of TNF-α inhibitor on diabetic nephropathy in rats
by: HOU Jia-sheng, et al.
Published: (2019-01-01)

Effect of long and short half-life PDE5 inhibitors on HbA1c levels: a systematic review and meta-analysisResearch in context
by: Joseph Kim, et al.
Published: (2025-02-01)

Efficacy and safety of PDE5 inhibitors in middle-aged and old patients with and without hypogonadism
by: Chunlin Wang, et al.
Published: (2024-12-01)

Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6
by: Ankit Joshi, et al.
Published: (2025-07-01)

Unveiling the Anti-Angiogenic Potential of Small-Molecule (Kinase) Inhibitors for Application in Rheumatoid Arthritis
by: Fatemeh Khodadust, et al.
Published: (2025-01-01)

Precision Medicine for Pediatric Glioma and NF1-Associated Tumors: The Role of Small Molecule Inhibitors
by: Samuele Renzi, et al.
Published: (2025-05-01)

NOD2-NLRP3 Axis and Asthma
by: Cai X
Published: (2025-05-01)

Correlation of Inflammasomes with Pyroptosis and Effect on Coagulation Function
by: GAO Jiawei, et al.
Published: (2024-11-01)

Effect of experimental gestational diabetes and administration of glibenclamide on mRNA level of NLRP3-inflammasome and distribution of NLRP3+-cells in mesenteric lymph nodes in progeny
by: Т. М. Prozorova, et al.
Published: (2017-08-01)

Evaluation of STK17B as a cancer immunotherapy target utilizing highly potent and selective small molecule inhibitors
by: Felix Scheuplein, et al.
Published: (2024-10-01)