Exogenous pyruvate is therapeutic against colitis by targeting cytosolic phospholipase A2
Ulcerative colitis is an idiopathic, chronic inflammatory bowel disease. Its pathogenesis is multifactorial involving inflammation and immune dysregulation. Proinflammatory TNFα/NFκB signaling is believed to play a cardinal role in ulcerative colitis. Growing evidence indicates the molecular interac...
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| Main Authors: | Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Chuan-ju Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2025-09-01
|
| Series: | Genes and Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352304225000601 |
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