Acupuncture treatment of Satoyoshi syndrome: a case report of a rare disease
BackgroundSatoyoshi syndrome (also known as Komuragaeri disease ) is a rare disorder of unknown etiology, with progressive muscle spasms, whole-body hair loss, and diarrhea as its main symptoms, particularly progressive skeletal muscle spasms and pain. Because of the lack of a clear etiology and pat...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2025.1543991/full |
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| author | Yu Gong Xudong Zhang Xiaomin Hao Jipeng Liu Bingnan Yue Chuan Liu Tianqi Xia Yi Yang Longteng Tu WeiJie Qiu Yu Liu Qingguo Liu |
| author_facet | Yu Gong Xudong Zhang Xiaomin Hao Jipeng Liu Bingnan Yue Chuan Liu Tianqi Xia Yi Yang Longteng Tu WeiJie Qiu Yu Liu Qingguo Liu |
| author_sort | Yu Gong |
| collection | DOAJ |
| description | BackgroundSatoyoshi syndrome (also known as Komuragaeri disease ) is a rare disorder of unknown etiology, with progressive muscle spasms, whole-body hair loss, and diarrhea as its main symptoms, particularly progressive skeletal muscle spasms and pain. Because of the lack of a clear etiology and pathogenesis of Satoyoshi syndrome, Western medicine lacks established effective therapies, and the long-term prognosis of the treatment of this disease is poor, unable to improve multiple symptoms simultaneously and prevent the recurrence of the disease. In recent years, acupuncture has been increasingly explored as a complementary treatment for autoimmune diseases. It is believed to exert its effects by modulating the neuroendocrine-immune network, enhancing immune cell function, and restoring homeostatic pathways. These mechanisms enable acupuncture to provide immune modulation, ultimately achieving a holistic and bidirectional regulatory effect.Case descriptionWe report the case of a 54-year-old male police officer who had Satoyoshi syndrome for more than five years. After six months of acupuncture treatment, the patient’s chronic diarrhea completely disappeared, and the occasional painful muscle cramps and insomnia significantly improved. After six months of follow-up, the patient’s condition was stable.ConclusionIn this study, we believe that acupuncture therapy is of great significance for the improvement of diarrhea, immediate and long-term analgesia, and stabilization of the Satoyoshi syndrome. |
| format | Article |
| id | doaj-art-81ae9f26199447fa8e96ff4ab1a436e8 |
| institution | DOAJ |
| issn | 1664-2392 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj-art-81ae9f26199447fa8e96ff4ab1a436e82025-08-20T03:22:19ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-05-011610.3389/fendo.2025.15439911543991Acupuncture treatment of Satoyoshi syndrome: a case report of a rare diseaseYu Gong0Xudong Zhang1Xiaomin Hao2Jipeng Liu3Bingnan Yue4Chuan Liu5Tianqi Xia6Yi Yang7Longteng Tu8WeiJie Qiu9Yu Liu10Qingguo Liu11School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaDepartment of Chinese Medicine, Beijing Jishuitan Hospital, Beijing, ChinaDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaDepartment of Acupuncture and Moxibustion, Beijing Chaoyang District Wangjing Community Health Service Center, Beijing, ChinaDepartment of Acupuncture and Moxibustion, Beijing Chaoyang District Wangjing Community Health Service Center, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaSchool of Special Education, Beijing Union University, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaBackgroundSatoyoshi syndrome (also known as Komuragaeri disease ) is a rare disorder of unknown etiology, with progressive muscle spasms, whole-body hair loss, and diarrhea as its main symptoms, particularly progressive skeletal muscle spasms and pain. Because of the lack of a clear etiology and pathogenesis of Satoyoshi syndrome, Western medicine lacks established effective therapies, and the long-term prognosis of the treatment of this disease is poor, unable to improve multiple symptoms simultaneously and prevent the recurrence of the disease. In recent years, acupuncture has been increasingly explored as a complementary treatment for autoimmune diseases. It is believed to exert its effects by modulating the neuroendocrine-immune network, enhancing immune cell function, and restoring homeostatic pathways. These mechanisms enable acupuncture to provide immune modulation, ultimately achieving a holistic and bidirectional regulatory effect.Case descriptionWe report the case of a 54-year-old male police officer who had Satoyoshi syndrome for more than five years. After six months of acupuncture treatment, the patient’s chronic diarrhea completely disappeared, and the occasional painful muscle cramps and insomnia significantly improved. After six months of follow-up, the patient’s condition was stable.ConclusionIn this study, we believe that acupuncture therapy is of great significance for the improvement of diarrhea, immediate and long-term analgesia, and stabilization of the Satoyoshi syndrome.https://www.frontiersin.org/articles/10.3389/fendo.2025.1543991/fullacupunctureSatoyoshi syndromecase reportrare diseaseautoimmune disorder |
| spellingShingle | Yu Gong Xudong Zhang Xiaomin Hao Jipeng Liu Bingnan Yue Chuan Liu Tianqi Xia Yi Yang Longteng Tu WeiJie Qiu Yu Liu Qingguo Liu Acupuncture treatment of Satoyoshi syndrome: a case report of a rare disease Frontiers in Endocrinology acupuncture Satoyoshi syndrome case report rare disease autoimmune disorder |
| title | Acupuncture treatment of Satoyoshi syndrome: a case report of a rare disease |
| title_full | Acupuncture treatment of Satoyoshi syndrome: a case report of a rare disease |
| title_fullStr | Acupuncture treatment of Satoyoshi syndrome: a case report of a rare disease |
| title_full_unstemmed | Acupuncture treatment of Satoyoshi syndrome: a case report of a rare disease |
| title_short | Acupuncture treatment of Satoyoshi syndrome: a case report of a rare disease |
| title_sort | acupuncture treatment of satoyoshi syndrome a case report of a rare disease |
| topic | acupuncture Satoyoshi syndrome case report rare disease autoimmune disorder |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2025.1543991/full |
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