Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer

Oral cancer continues to cause profound suffering and is associated with high mortality rates. Early detection techniques are crucial in enhancing patient outcomes. This review paper thoroughly evaluates the significance of biomarkers and recent advancements in oral cancer detection, emphasizing cut...

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Main Authors: Sanket Naresh Nagdeve, Baviththira Suganthan, Ramaraja P. Ramasamy
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/25/5/1459
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author Sanket Naresh Nagdeve
Baviththira Suganthan
Ramaraja P. Ramasamy
author_facet Sanket Naresh Nagdeve
Baviththira Suganthan
Ramaraja P. Ramasamy
author_sort Sanket Naresh Nagdeve
collection DOAJ
description Oral cancer continues to cause profound suffering and is associated with high mortality rates. Early detection techniques are crucial in enhancing patient outcomes. This review paper thoroughly evaluates the significance of biomarkers and recent advancements in oral cancer detection, emphasizing cutting-edge electrochemical methods. The paper provides an epidemiological and etiological overview, outlining its clinical importance and reviewing the current state of the art in detection methods. Despite considerable progress, conventional methods exhibit limitations such as invasiveness, long wait times, and a lack of accuracy, creating a critical need for more robust technologies. This review emphasizes the significance of oral cancer biomarkers, which are considered promising cues for early detection, facilitating the development of innovative biosensing technologies. This review seeks to illuminate the recent advances in early detection and precision diagnostics, along with the usage of artificial intelligence strategies, ultimately contributing to significant progress in the battle against oral cancer.
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spelling doaj-art-819f4e85f7884465a7c5ffe5e196fb322025-08-20T02:53:22ZengMDPI AGSensors1424-82202025-02-01255145910.3390/s25051459Perspectives on the Application of Biosensors for the Early Detection of Oral CancerSanket Naresh Nagdeve0Baviththira Suganthan1Ramaraja P. Ramasamy2Nano Electrochemistry Laboratory, School of Chemical, Materials and Biomedical Engineering, University of Georgia, Athens, GA 30602, USANano Electrochemistry Laboratory, School of Chemical, Materials and Biomedical Engineering, University of Georgia, Athens, GA 30602, USANano Electrochemistry Laboratory, School of Chemical, Materials and Biomedical Engineering, University of Georgia, Athens, GA 30602, USAOral cancer continues to cause profound suffering and is associated with high mortality rates. Early detection techniques are crucial in enhancing patient outcomes. This review paper thoroughly evaluates the significance of biomarkers and recent advancements in oral cancer detection, emphasizing cutting-edge electrochemical methods. The paper provides an epidemiological and etiological overview, outlining its clinical importance and reviewing the current state of the art in detection methods. Despite considerable progress, conventional methods exhibit limitations such as invasiveness, long wait times, and a lack of accuracy, creating a critical need for more robust technologies. This review emphasizes the significance of oral cancer biomarkers, which are considered promising cues for early detection, facilitating the development of innovative biosensing technologies. This review seeks to illuminate the recent advances in early detection and precision diagnostics, along with the usage of artificial intelligence strategies, ultimately contributing to significant progress in the battle against oral cancer.https://www.mdpi.com/1424-8220/25/5/1459biomarkersbiofluidselectrochemical sensorsmolecular analytical techniquesdiagnostic toolscommercial test kits
spellingShingle Sanket Naresh Nagdeve
Baviththira Suganthan
Ramaraja P. Ramasamy
Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer
Sensors
biomarkers
biofluids
electrochemical sensors
molecular analytical techniques
diagnostic tools
commercial test kits
title Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer
title_full Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer
title_fullStr Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer
title_full_unstemmed Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer
title_short Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer
title_sort perspectives on the application of biosensors for the early detection of oral cancer
topic biomarkers
biofluids
electrochemical sensors
molecular analytical techniques
diagnostic tools
commercial test kits
url https://www.mdpi.com/1424-8220/25/5/1459
work_keys_str_mv AT sanketnareshnagdeve perspectivesontheapplicationofbiosensorsfortheearlydetectionoforalcancer
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AT ramarajapramasamy perspectivesontheapplicationofbiosensorsfortheearlydetectionoforalcancer