Microvascular angina in postmenopausal women.
<strong>Background:</strong> Microvascular angina is common in postmenopausal women. Myocardial ischemia has been induced by stress testing, which has proved a relationship between endothelial dysfunction and myocardial perfusion defects. <br /><strong>Objective:</strong&g...
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2011-10-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/1513 |
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| author | Alexander Valdés Martín Sherien Sixto Fernández |
| author_facet | Alexander Valdés Martín Sherien Sixto Fernández |
| author_sort | Alexander Valdés Martín |
| collection | DOAJ |
| description | <strong>Background:</strong> Microvascular angina is common in postmenopausal women. Myocardial ischemia has been induced by stress testing, which has proved a relationship between endothelial dysfunction and myocardial perfusion defects. <br /><strong>Objective:</strong> To determine whether myocardial ischemia can be evidenced by abnormalities of perfusion and function detected by myocardial scintigraphy in women with typical angina, normal coronary angiography and endothelial dysfunction. <strong><br />Methods:</strong> A descriptive study was conducted at the Cardiology and Cardiovascular Surgery Institute in Havana. These women were tested for lipid profile. Endothelial function was measured in the brachial artery by ultrasound, and a 24 hours (Holter) lectrocardiographic study. A stress-rest protocol during scan was used. Patients were divided into two groups according to presence (group I) or absence (group II) of myocardial perfusion defects. <strong><br />Results:</strong> 21 patients presented perfusion defects. In group I, 57% of patients presented more endothelial dysfunction. Only twelve patients showed reversible defects of perfusion and 75% of these cases were associated with a reduction in left ventricular ejection fraction of post-stress over 5% and regional abnormalities of wall motion. Three patients in group I showed evidence of ischemia compared to four others in group II. <strong><br />Conclusions:</strong> Stress-induced ischemia is associated with a post-stress reduction in left ventricular ejection fraction and an abnormal endothelium-dependent vasodilation. |
| format | Article |
| id | doaj-art-819514523c1a411598c2e550674903af |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2011-10-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-819514523c1a411598c2e550674903af2025-01-30T21:28:44ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2011-10-0195443451784Microvascular angina in postmenopausal women.Alexander Valdés Martín0Sherien Sixto Fernández1Instituto de Cardiología y Cirugía Cardiovascular. La Habana.Instituto de Cardiología y Cirugía Cardiovascular. La Habana.<strong>Background:</strong> Microvascular angina is common in postmenopausal women. Myocardial ischemia has been induced by stress testing, which has proved a relationship between endothelial dysfunction and myocardial perfusion defects. <br /><strong>Objective:</strong> To determine whether myocardial ischemia can be evidenced by abnormalities of perfusion and function detected by myocardial scintigraphy in women with typical angina, normal coronary angiography and endothelial dysfunction. <strong><br />Methods:</strong> A descriptive study was conducted at the Cardiology and Cardiovascular Surgery Institute in Havana. These women were tested for lipid profile. Endothelial function was measured in the brachial artery by ultrasound, and a 24 hours (Holter) lectrocardiographic study. A stress-rest protocol during scan was used. Patients were divided into two groups according to presence (group I) or absence (group II) of myocardial perfusion defects. <strong><br />Results:</strong> 21 patients presented perfusion defects. In group I, 57% of patients presented more endothelial dysfunction. Only twelve patients showed reversible defects of perfusion and 75% of these cases were associated with a reduction in left ventricular ejection fraction of post-stress over 5% and regional abnormalities of wall motion. Three patients in group I showed evidence of ischemia compared to four others in group II. <strong><br />Conclusions:</strong> Stress-induced ischemia is associated with a post-stress reduction in left ventricular ejection fraction and an abnormal endothelium-dependent vasodilation.http://medisur.sld.cu/index.php/medisur/article/view/1513isquemia miocárdicaestrés fisiológicoprueba de esfuerzovolumen sistólicovasodilatación |
| spellingShingle | Alexander Valdés Martín Sherien Sixto Fernández Microvascular angina in postmenopausal women. Medisur isquemia miocárdica estrés fisiológico prueba de esfuerzo volumen sistólico vasodilatación |
| title | Microvascular angina in postmenopausal women. |
| title_full | Microvascular angina in postmenopausal women. |
| title_fullStr | Microvascular angina in postmenopausal women. |
| title_full_unstemmed | Microvascular angina in postmenopausal women. |
| title_short | Microvascular angina in postmenopausal women. |
| title_sort | microvascular angina in postmenopausal women |
| topic | isquemia miocárdica estrés fisiológico prueba de esfuerzo volumen sistólico vasodilatación |
| url | http://medisur.sld.cu/index.php/medisur/article/view/1513 |
| work_keys_str_mv | AT alexandervaldesmartin microvascularanginainpostmenopausalwomen AT sheriensixtofernandez microvascularanginainpostmenopausalwomen |