Remodeling of ER Membrane Contact Sites During Cell Division
Membrane contact sites (MCS) provide specialized conduits for inter-organelle communications to maintain cellular homeostasis. Most organelles are interconnected, which supports their coordination and function. M-phase (mitosis or meiosis) is associated with dramatic cellular remodeling to support c...
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| Language: | English |
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SAGE Publishing
2025-01-01
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| Online Access: | https://doi.org/10.1177/25152564241309207 |
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| _version_ | 1832582692083859456 |
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| author | Fang Yu Khaled Machaca |
| author_facet | Fang Yu Khaled Machaca |
| author_sort | Fang Yu |
| collection | DOAJ |
| description | Membrane contact sites (MCS) provide specialized conduits for inter-organelle communications to maintain cellular homeostasis. Most organelles are interconnected, which supports their coordination and function. M-phase (mitosis or meiosis) is associated with dramatic cellular remodeling to support cell division, including the equal distribution of organelles to the two daughter cells. However, the fate of MCS in M-phase is poorly understood. Here we review recent advances arguing for differential remodeling of endoplasmic reticulum (ER) MCS with the plasma membrane (PM, ERPMCS) and the mitochondria (MERCS) during cell division. |
| format | Article |
| id | doaj-art-8182651764b946e7bc8d18c14925a3fa |
| institution | Kabale University |
| issn | 2515-2564 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Contact |
| spelling | doaj-art-8182651764b946e7bc8d18c14925a3fa2025-01-29T12:04:17ZengSAGE PublishingContact2515-25642025-01-01810.1177/25152564241309207Remodeling of ER Membrane Contact Sites During Cell DivisionFang Yu0Khaled Machaca1 Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USAMembrane contact sites (MCS) provide specialized conduits for inter-organelle communications to maintain cellular homeostasis. Most organelles are interconnected, which supports their coordination and function. M-phase (mitosis or meiosis) is associated with dramatic cellular remodeling to support cell division, including the equal distribution of organelles to the two daughter cells. However, the fate of MCS in M-phase is poorly understood. Here we review recent advances arguing for differential remodeling of endoplasmic reticulum (ER) MCS with the plasma membrane (PM, ERPMCS) and the mitochondria (MERCS) during cell division.https://doi.org/10.1177/25152564241309207 |
| spellingShingle | Fang Yu Khaled Machaca Remodeling of ER Membrane Contact Sites During Cell Division Contact |
| title | Remodeling of ER Membrane Contact Sites During Cell Division |
| title_full | Remodeling of ER Membrane Contact Sites During Cell Division |
| title_fullStr | Remodeling of ER Membrane Contact Sites During Cell Division |
| title_full_unstemmed | Remodeling of ER Membrane Contact Sites During Cell Division |
| title_short | Remodeling of ER Membrane Contact Sites During Cell Division |
| title_sort | remodeling of er membrane contact sites during cell division |
| url | https://doi.org/10.1177/25152564241309207 |
| work_keys_str_mv | AT fangyu remodelingofermembranecontactsitesduringcelldivision AT khaledmachaca remodelingofermembranecontactsitesduringcelldivision |