Monoclonal antibody for phosphorylated TRIO Y2681 that helps predict prognosis of post-operative colorectal cancer patients

Monoclonal antibody for phosphorylated TRIO Y2681 that helps predict prognosis of post-operative colorectal cancer patients

Abstract Background We previously reported that TRIO pY2681, a novel prognostic biomarker for CRC, can be detected by polyclonal antibodies (pAb). We have now developed a novel monoclonal antibody (mAb) that recognizes TRIO pY2681. This study aims to assess the utility of immunohistochemical (IHC) s...

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Main Authors: Taro Aoyama, Fumihiko Kakizaki, Hiroyuki Miyoshi, Masahiro Sonoshita, Hisatsugu Maekawa, Yoshiro Itatani, Kenji Kawada, Ryo Matsusue, Iwao Ikai, Koki Moriyoshi, Takaki Sakurai, Kazutaka Obama, Tosiya Shun Sato, Yoshiharu Sakai, Makoto Mark Taketo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:BJC Reports
Online Access:https://doi.org/10.1038/s44276-025-00163-0
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