Actively protective combinatorial analysis: A scalable novel method for detecting variants that contribute to reduced disease prevalence in high-risk individuals
We present a novel method for routinely identifying disease resilience associations that offers powerful insights for the discovery of a new class of disease protective targets. We show how this can be used to identify mechanisms in the background of normal cellular biology that work to slow or stop...
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Main Authors: | J Sardell, S Das, K Taylor, C Stubberfield, A Malinowski, M Strivens, S Gardner |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-06-01
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Series: | Artificial Intelligence in the Life Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667318525000017 |
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