Development of Immunocapture-LC/MS Assay for Simultaneous ADA Isotyping and Semiquantitation

Therapeutic proteins and peptides have potential to elicit immune responses resulting in anti-drug antibodies that can pose problems for both patient safety and product efficacy. During drug development immunogenicity is usually examined by risk-based approach along with specific strategies for deve...

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Bibliographic Details
Main Authors: Lin-Zhi Chen, David Roos, Elsy Philip
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/7682472
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