Development of Immunocapture-LC/MS Assay for Simultaneous ADA Isotyping and Semiquantitation
Therapeutic proteins and peptides have potential to elicit immune responses resulting in anti-drug antibodies that can pose problems for both patient safety and product efficacy. During drug development immunogenicity is usually examined by risk-based approach along with specific strategies for deve...
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| Main Authors: | Lin-Zhi Chen, David Roos, Elsy Philip |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2016/7682472 |
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