Dravet Syndrome: A Rare Form of Epilepsy

Dravet syndrome is a rare and severe form of epilepsy that usually emerges in infancy. It is characterized by diverse seizure patterns, cognitive regression, motor impairments, and behavioral abnormalities. The majority of patients with this condition have mutations involving the voltage-gated sodiu...

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Main Authors: Salwa Al Hosani, Sona Varghese
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2024/6710512
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author Salwa Al Hosani
Sona Varghese
author_facet Salwa Al Hosani
Sona Varghese
author_sort Salwa Al Hosani
collection DOAJ
description Dravet syndrome is a rare and severe form of epilepsy that usually emerges in infancy. It is characterized by diverse seizure patterns, cognitive regression, motor impairments, and behavioral abnormalities. The majority of patients with this condition have mutations involving the voltage-gated sodium channel alpha (I) gene SCN1A. We present a detailed account of a two-year-old child with a history of recurrent seizures since the age of 4 months. Genetic testing was performed which revealed a heterozygous pathogenic variant, confirming the diagnosis. The patient was managed successfully by a multidisciplinary approach involving neurologists, developmental specialists, and physical therapists.
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institution Kabale University
issn 1687-9635
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spelling doaj-art-8170c1d4e6774115be8e2c7bc98aca142025-08-20T03:35:07ZengWileyCase Reports in Medicine1687-96352024-01-01202410.1155/2024/6710512Dravet Syndrome: A Rare Form of EpilepsySalwa Al Hosani0Sona Varghese1Department of PsychiatryDepartment of PsychiatryDravet syndrome is a rare and severe form of epilepsy that usually emerges in infancy. It is characterized by diverse seizure patterns, cognitive regression, motor impairments, and behavioral abnormalities. The majority of patients with this condition have mutations involving the voltage-gated sodium channel alpha (I) gene SCN1A. We present a detailed account of a two-year-old child with a history of recurrent seizures since the age of 4 months. Genetic testing was performed which revealed a heterozygous pathogenic variant, confirming the diagnosis. The patient was managed successfully by a multidisciplinary approach involving neurologists, developmental specialists, and physical therapists.http://dx.doi.org/10.1155/2024/6710512
spellingShingle Salwa Al Hosani
Sona Varghese
Dravet Syndrome: A Rare Form of Epilepsy
Case Reports in Medicine
title Dravet Syndrome: A Rare Form of Epilepsy
title_full Dravet Syndrome: A Rare Form of Epilepsy
title_fullStr Dravet Syndrome: A Rare Form of Epilepsy
title_full_unstemmed Dravet Syndrome: A Rare Form of Epilepsy
title_short Dravet Syndrome: A Rare Form of Epilepsy
title_sort dravet syndrome a rare form of epilepsy
url http://dx.doi.org/10.1155/2024/6710512
work_keys_str_mv AT salwaalhosani dravetsyndromearareformofepilepsy
AT sonavarghese dravetsyndromearareformofepilepsy